Oxidative stress in cardiovascular diseases: still a therapeutic target?

T Senoner, W Dichtl - Nutrients, 2019 - mdpi.com
Cardiovascular diseases (CVD) are complex entities with heterogenous pathophysiologic
mechanisms and increased oxidative stress has been viewed as one of the potential …

Effects of tobacco smoking on cardiovascular disease

T Kondo, Y Nakano, S Adachi, T Murohara - Circulation Journal, 2019 - jstage.jst.go.jp
Tobacco smoking continues to be a major risk factor for cardiovascular disease (CVD) and
the leading avoidable cause of death worldwide. Tobacco smoking has declined in high …

[HTML][HTML] ESVM Guideline on peripheral arterial disease

U Frank, S Nikol, J Belch, V Boc, M Brodmann… - Vasa, 2019 - econtent.hogrefe.com
The European Society of Vascular Medicine (ESVM) was founded in Paris in 2012 as a
confederation of already existing and emerging European societies of vascular medicine. At …

Endothelial cell metabolism

G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation

FWJ Chioh, SW Fong, BE Young, KX Wu, A Siau… - Elife, 2021 - elifesciences.org
Numerous reports of vascular events after an initial recovery from COVID-19 form our
impetus to investigate the impact of COVID-19 on vascular health of recovered patients. We …

Aldosterone as a mediator of cardiovascular damage

F Buffolo, M Tetti, P Mulatero, S Monticone - Hypertension, 2022 - Am Heart Assoc
Besides the physiological regulation of water, sodium, and potassium homeostasis,
aldosterone modulates several physiological and pathological processes in the …

The tissue-engineered vascular graft—past, present, and future

S Pashneh-Tala, S MacNeil… - Tissue Engineering Part B …, 2016 - liebertpub.com
Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Targeting vascular (endothelial) dysfunction

A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …