The epidemiology of esophageal adenocarcinoma

HG Coleman, SH Xie, J Lagergren - Gastroenterology, 2018 - Elsevier
The incidence of esophageal adenocarcinoma (EAC) has increased in many Western
countries and is higher in men than women. Some risk factors for EAC have been identified …

Oesophageal cancer

J Lagergren, E Smyth, D Cunningham, P Lagergren - The Lancet, 2017 - thelancet.com
Oesophageal cancer is a clinically challenging disease that requires a multidisciplinary
approach. Extensive treatment might be associated with a considerable decline in health …

[HTML][HTML] A randomized clinical trial of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the oesophagus or gastro-oesophageal …

F Klevebro, GA von Döbeln, N Wang, G Johnsen… - Annals of …, 2016 - Elsevier
Background Neoadjuvant therapy improves long-term survival after oesophagectomy,
treating oesophageal cancer, but the evidence to date is insufficient to determine which of …

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

M Wu, Y Wang, D Yang, Y Gong, F Rao, R Liu… - …, 2019 - thelancet.com
Background Targeting PLK1 has recently been proven as a viable therapeutic strategy
against oesophageal squamous cell carcinom (ESCC). Therefore, this study aimed to …

Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

N Murugaesu, GA Wilson, NJ Birkbak, TBK Watkins… - Cancer discovery, 2015 - AACR
Esophageal adenocarcinomas are associated with a dismal prognosis. Deciphering the
evolutionary history of this disease may shed light on therapeutically tractable targets and …

[HTML][HTML] Exercise prehabilitation during neoadjuvant chemotherapy may enhance tumour regression in oesophageal cancer: results from a prospective non …

J Zylstra, GP Whyte, K Beckmann, J Pate… - British Journal of …, 2022 - bjsm.bmj.com
Background There is increasing evidence for the use of exercise in cancer patients and data
supporting enhanced tumour volume reduction following chemotherapy in animal models …

Integrated PPI-and WGCNA-retrieval of hub gene signatures shared between Barrett's esophagus and esophageal adenocarcinoma

AS Nangraj, G Selvaraj, S Kaliamurthi… - Frontiers in …, 2020 - frontiersin.org
Esophageal adenocarcinoma (EAC) is a deadly cancer with high mortality rate, especially in
economically advanced countries, while Barrett's esophagus (BE) is reported to be a …

Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma

F Noble, MA Lloyd, R Turkington… - Journal of British …, 2017 - academic.oup.com
Background This multicentre cohort study sought to define a robust pathological indicator of
clinically meaningful response to neoadjuvant chemotherapy in oesophageal …

Extent of lymphadenectomy and prognosis after esophageal cancer surgery

J Lagergren, F Mattsson, J Zylstra, F Chang… - JAMA …, 2016 - jamanetwork.com
Importance The prognostic role of the extent of lymphadenectomy during surgery for
esophageal cancer is uncertain and requires clarification. Objective To clarify whether the …

Cell membrane-based biomimetic nanosystems for advanced drug delivery in cancer therapy: A comprehensive review

J Zhao, J Ruan, G Lv, Q Shan, Z Fan, H Wang… - Colloids and Surfaces B …, 2022 - Elsevier
Natural types of cells display distinct characteristics with homotypic targeting and extended
circulation in the blood, which are worthy of being explored as promising drug delivery …