State-of-the-art and recent developments of immobilized polysaccharide-based chiral stationary phases for enantioseparations by high-performance liquid …

JM Padró, S Keunchkarian - Microchemical Journal, 2018 - Elsevier
Polysaccharide-based chiral stationary phases have been recognized as one of the most
powerful ones for high performance liquid chromatography (HPLC) separations of chiral …

State-of-the-art enantioseparations of natural and unnatural amino acids by high-performance liquid chromatography

I Ilisz, A Péter, W Lindner - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
This review discusses recent publications on the separation and analysis of natural and
unnatural amino acid enantiomers by liquid chromatography. Focus is placed on …

Liquid chromatographic enantiomer separations applying chiral ion-exchangers based on Cinchona alkaloids

I Ilisz, A Bajtai, W Lindner, A Péter - Journal of Pharmaceutical and …, 2018 - Elsevier
As the understanding of the various biological actions of compounds with different
stereochemistry has grown, the necessity to develop methods for the analytical qualification …

Recentchiral selectors for separation in HPLC and CE

K Kalíková, M Riesová, E Tesařová - Open Chemistry, 2012 - degruyter.com
Enantiomers (stereoisomers) can exhibit substantially different properties if present in chiral
environments. Since chirality is a basic property of nature, the different behaviors of the …

Chiral x achiral multidimensional liquid chromatography. Application to the enantioseparation of dintitrophenyl amino acids in honey samples and their fingerprint …

A Acquaviva, G Siano, P Quintas, MR Filgueira… - … of Chromatography A, 2020 - Elsevier
Most HPLC enantiomer separations are performed with columns packed with a chiral
stationary phase (CSP) operated with an achiral mobile phase. The intrinsically limited …

Synthesis and performance of chiral ferrocene modified silica gel for mixed-mode chromatography

L Qiao, X Zhou, X Li, W Du, A Yu, S Zhang, Y Wu - Talanta, 2017 - Elsevier
A brush-type chiral stationary phase, N-ferrocenyl benzoyl-(1S, 2R)-1, 2-diphenyl ethanol-
bonded on the silica gel (NFcBEs) for high performance liquid chromatography (HPLC), was …

Synthesis of novel chiral imidazolium stationary phases and their enantioseparation evaluation by high-performance liquid chromatography

T Wang, H Yang, R Qiu, S Huang - Analytica Chimica Acta, 2016 - Elsevier
Two novel chiral stationary phases (CSPs) were prepared by bonding chiral imidazoliums
on the surface of silica gel. The chiral imidazoles were derivatized from chiral amines, 1 …

Synthesis and characterization of chiral ionic liquids based on quinine, L-proline and L-valine for enantiomeric recognition

TE Sintra, MG Gantman, SPM Ventura… - Journal of Molecular …, 2019 - Elsevier
The separation of enantiomers remains a major challenge for the pharmaceutical industry. In
this work, eight chiral ionic liquids (CILs) directly derived from the 'chiral pool'were …

Enantioseparation of α-amino acids by means of Cinchona alkaloids as selectors in chiral ligand-exchange chromatography

S Keunchkarian, CA Franca, LG Gagliardi… - … of Chromatography A, 2013 - Elsevier
A conventional nonchiral column was used for the enantioseparation of several racemic α-
amino acids (native and derivatized) through the use of Cinchona alkaloids as chiral …

Preparation and evaluation of novel chiral stationary phases based on quinine derivatives comprising crown ether moieties

D Wang, J Zhao, H Wu, H Wu, J Cai… - Journal of Separation …, 2015 - Wiley Online Library
The C9‐position of quinine was modified by meta‐or para‐substituted benzo‐18‐crown‐6,
and immobilized on 3‐mercaptopropyl‐modified silica gel through the radical thiol‐ene …