Abstract Calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) is the most
abundant protein in excitatory synapses and is central to synaptic plasticity, learning and …

Long-term potentiation (LTP) of synaptic strength occurs during learning and can last for
long periods, making it a probable mechanism for memory storage. LTP induction results in …

Calcium/calmodulin-stimulated protein kinase II (CaMKII) is a family of broad substrate
specificity serine (Ser)/threonine (Thr) protein kinases widely expressed in many tissues that …

Excitatory (glutamatergic) synapses in the mammalian brain are usually situated on dendritic
spines, a postsynaptic microcompartment that also harbors organelles involved in protein …

Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key protein kinase in neural
plasticity and memory, as have been shown in several studies since the first evidence in …

In the nervous system, many intracellular responses to elevated calcium are mediated by
CaM kinases (CaMKs), a family of protein kinases whose activities are initially modulated by …

In this article the calcium/calmodulin-dependent protein kinases are reviewed. The primary
focus is on the structure and function of this diverse family of enzymes, and the elegant …

Learning and memory require the formation of new neural networks in the brain. A key
mechanism underlying this process is synaptic plasticity at excitatory synapses, which …

Among diverse factors regulating excitatory synaptic transmission, the abundance of
postsynaptic glutamate receptors figures prominently in molecular memory and learning …

Long-term potentiation (LTP), a long-lasting enhancement in communication between
neurons, is considered to be the major cellular mechanism underlying learning and memory …