Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

The BCL-2 family of proteins controls cell death primarily by direct binding interactions that
regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible …

Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of
renal tubular cells may occur by apoptosis during developmental and regenerative …

FÖrster resonance energy transfer (FRET)-based biosensors have achieved great success
for biological applications. However, what is not extensively appreciated is the growing role …

This critical review provides an overview of the continually expanding family of fluorescent
proteins (FPs) that have become essential tools for studies of cell biology and physiology …

Fluorescent probes are one of the cornerstones of real-time imaging of live cells and a
powerful tool for cell biologists. They provide high sensitivity and great versatility while …

Nanoparticles have unique capacities of interacting with the cellular machinery and entering
cells. To be able to exploit this potential, it is essential to understand what controls the …

Although apoptosis and necrosis have distinct features, the identification and discrimination
of apoptotic and necrotic cell death in vitro is challenging. Immunocytological and …

Apoptosis pathways activated by death receptors of the tumour necrosis factor (TNF) family
such as Fas, TNFR1, or the TRAIL receptors DR4 and DR5 are implicated in diverse …