Molecular farming on rescue of pharma industry for next generations

K Moustafa, A Makhzoum… - Critical reviews in …, 2016 - Taylor & Francis
Recombinant proteins expressed in plants have been emerged as a novel branch of the
biopharmaceutical industry, offering practical and safety advantages over traditional …

Pharming and transgenic plants

D Lienard, C Sourrouille, V Gomord, L Faye - Biotechnology Annual Review, 2007 - Elsevier
Plant represented the essence of pharmacopoeia until the beginning of the 19th century
when plant-derived pharmaceuticals were partly supplanted by drugs produced by the …

Oral immunization with transgenic rice seeds expressing VP2 protein of infectious bursal disease virus induces protective immune responses in chickens

J Wu, L Yu, L Li, J Hu, J Zhou… - Plant Biotechnology …, 2007 - Wiley Online Library
The expression of infectious bursal disease virus (IBDV) host‐protective immunogen VP2
protein in rice seeds, its immunogenicity and protective capability in chickens were …

Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview

DM Floss, D Falkenburg, U Conrad - Transgenic research, 2007 - Springer
During the past two decades, antibodies, antibody derivatives and vaccines have been
developed for therapeutic and diagnostic applications in human and veterinary medicine …

Advances in vaccine research against economically important viral diseases of food animals: Infectious bursal disease virus

DJ Jackwood - Veterinary microbiology, 2017 - Elsevier
Numerous reviews have been published on infectious bursal disease (IBD) and infectious
bursal disease virus (IBDV). Many high quality vaccines are commercially available for the …

Development of a recombinant VP2 vaccine for the prevention of novel variant strains of infectious bursal disease virus

G Li, H Kuang, H Guo, L Cai, D Chu, X Wang… - Avian …, 2020 - Taylor & Francis
Since 2017, novel variant strains of infectious bursal disease virus (nvIBDV) have been
detected in China, while the current vaccines on the market against very virulent IBDV have …

Smallpox subunit vaccine produced in planta confers protection in mice

M Golovkin, S Spitsin, V Andrianov… - Proceedings of the …, 2007 - National Acad Sciences
We report here the in planta production of the recombinant vaccinia virus B5 antigenic
domain (pB5), an attractive component of a subunit vaccine against smallpox. The antigenic …

Farming of plant‐based veterinary vaccines and their applications for disease prevention in animals

PS Liew, M Hair-Bejo - Advances in virology, 2015 - Wiley Online Library
Plants have been studied for the production of pharmaceutical compounds for more than two
decades now. Ever since the plant‐made poultry vaccine against Newcastle disease virus …

Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against infectious bursal disease virus

E Gómez, MS Lucero, SC Zoth, JM Carballeda… - Vaccine, 2013 - Elsevier
Infectious Bursal Disease Virus (IBDV) is the etiological agent of an immunosuppressive and
highly contagious disease that affects young birds. This disease causes important economic …

Improving containment strategies in biopharming

DJ Murphy - Plant Biotechnology Journal, 2007 - Wiley Online Library
This review examines the challenges of segregating biopharmed crops expressing
pharmaceutical or veterinary agents from mainstream crops, particularly those destined for …