Role of NLRP3 Inflammasome in post-spinal-cord-injury anxiety and depression: molecular mechanisms and therapeutic implications

T Mokhtari, K Uludag - ACS Chemical Neuroscience, 2023 - ACS Publications
The majority of research on the long-term effects of spinal cord injury (SCI) has primarily
focused on neuropathic pain (NP), psychological issues, and sensorimotor impairments …

Data-driven prediction of spinal cord injury recovery: An exploration of current status and future perspectives

S Håkansson, M Tuci, M Bolliger, A Curt… - Experimental …, 2024 - Elsevier
Abstract Spinal Cord Injury (SCI) presents a significant challenge in rehabilitation medicine,
with recovery outcomes varying widely among individuals. Machine learning (ML) is a …

Prognostic value of tissue bridges in cervical spinal cord injury: a longitudinal, multicentre, retrospective cohort study

D Pfyffer, AC Smith, KA Weber, A Grillhoesl… - The Lancet …, 2024 - thelancet.com
Background The accuracy of prognostication in patients with cervical spinal cord injury (SCI)
needs to be improved. We aimed to explore the prognostic value of preserved spinal tissue …

[HTML][HTML] Acute implantation of a bioresorbable polymer scaffold in patients with complete thoracic spinal cord injury: 24-month follow-up from the INSPIRE study

KD Kim, KS Lee, D Coric, JS Harrop, N Theodore… - …, 2022 - journals.lww.com
BACKGROUND: Based on 6-month data from the InVivo Study of Probable Benefit of the
Neuro-Spinal Scaffold for Safety and Neurological Recovery in Patients with Complete …

Finger somatotopy is preserved after tetraplegia but deteriorates over time

S Kikkert, D Pfyffer, M Verling, P Freund, N Wenderoth - Elife, 2021 - elifesciences.org
Previous studies showed reorganised and/or altered activity in the primary sensorimotor
cortex after a spinal cord injury (SCI), suggested to reflect abnormal processing. However …

Sciseg: Automatic segmentation of intramedullary lesions in spinal cord injury on t2-weighted mri scans

E Naga Karthik, J Valošek, AC Smith… - Radiology: Artificial …, 2024 - pubs.rsna.org
Purpose To develop a deep learning tool for the automatic segmentation of the spinal cord
and intramedullary lesions in spinal cord injury (SCI) on T2-weighted MRI scans. Materials …

Stimulation of the cuneiform nucleus enables training and boosts recovery after spinal cord injury

AS Hofer, MI Scheuber, AM Sartori, N Good, SA Stalder… - Brain, 2022 - academic.oup.com
Severe spinal cord injuries result in permanent paraparesis in spite of the frequent sparing
of small portions of white matter. Spared fibre tracts are often incapable of maintaining and …

Improving diagnostic workup following traumatic spinal cord injury: advances in biomarkers

S Schading, TM Emmenegger, P Freund - Current neurology and …, 2021 - Springer
Abstract Purpose of Review Traumatic spinal cord injury (SCI) is a life-changing event with
drastic implications for patients due to sensorimotor impairment and autonomous …

Transcutaneous electrical spinal cord stimulation to promote recovery in chronic spinal cord injury

C Tefertiller, M Rozwod, E VandeGriend… - Frontiers in …, 2022 - frontiersin.org
Objective: To evaluate the impact of using transcutaneous electrical spinal cord stimulation
(TSCSTSCS) on upper and lower extremity function in individuals with chronic spinal cord …

Longitudinal motor system changes from acute to chronic spinal cord injury

TM Emmenegger, D Pfyffer, A Curt… - European Journal of …, 2024 - Wiley Online Library
Background and purpose In acute spinal cord injury (SCI), magnetic resonance imaging
(MRI) reveals tissue bridges and neurodegeneration for 2 years. This 5‐year study aims to …