Unhealthy lifestyle choices, poor diet, and aging can have negative influences on cognition,
gradually increasing the risk for mild cognitive impairment (MCI) and the continuum …

Alzheimer's disease (AD) poses a critical public health challenge, and there is an urgent
need for novel treatment options. Glutamate, the principal excitatory neurotransmitter in the …

Traumatic brain injury (TBI) causes progressive dysfunction that induces biochemical and
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …

Glioma is a common and fatal malignant primary brain tumor. Radiotherapy and first-line
chemotherapy have little effect on the survival rate of patients, requiring alternative …

Neuron-derived orphan receptor 1 (NOR1), also called nuclear receptor subfamily 4 group A
member 3 (NR4A3), is a nuclear receptor belonging to the NR4A family. Since no …

Quantitative PCR (qPCR) is a widely used method to study gene expression changes
following brain injury. The accuracy of this method depends on the tissue harvested, the time …

Clinically, ischemic stroke is a serious disease hard to cure, therefore it is of great
importance to slow down the depletion of ATP to enhance the tolerance of ischemic tissue …