The dual personality of NO

M Colasanti, H Suzuki - Trends in pharmacological sciences, 2000 - cell.com
In the body, nitric oxide (NO) is an important physiological regulator of functions such as
vasodilatation and neurotransmission. Under pathological conditions, high concentrations of …

Molecular control of nitric oxide synthases in the cardiovascular system

A Papapetropoulos, RD Rudic… - Cardiovascular …, 1999 - academic.oup.com
Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the
regulation of the three nitric oxide synthase isoforms in the cardiovascular system are …

[HTML][HTML] Nitric oxide mediates anti-inflammatory action of extracorporeal shock waves

AR Ciampa, AC de Prati, E Amelio, E Cavalieri… - FEBS letters, 2005 - Elsevier
Here, we show that extracorporeal shock waves (ESW), at a low energy density value,
quickly increase neuronal nitric oxide synthase (nNOS) activity and basal nitric oxide (NO) …

Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation

A Conti, M Miscusi, S Cardali, A Germanò… - Brain Research …, 2007 - Elsevier
Nitric oxide (NO) is a unique informational molecule involved in a variety of physiological
processes in the central nervous system (CNS). It has been demonstrated that it can exert …

Reactive nitrogen and oxygen species in airway inflammation

G Folkerts, J Kloek, RBR Muijsers… - European journal of …, 2001 - Elsevier
The free radical nitric oxide (NO) is an important mediator of many biological processes.
Interestingly, the molecule appears to be a two-edged sword. Apart from NO having a …

[PDF][PDF] Immune processes in the pathogenesis of Parkinson's disease-a potential role for microglia and nitric oxide

A Czlonkowska, I Kurkowska-Jastrzebska… - Medical Science …, 2002 - researchgate.net
It has been known for many years that immune system alterations occur in Parkinson's
disease (PD). Changes in lymphocyte populations in cerebrospinal fluid and blood …

A pivotal role of endothelial-specific NF-κB signaling in the pathogenesis of septic shock and septic vascular dysfunction

J Ding, D Song, X Ye, SF Liu - The Journal of Immunology, 2009 - journals.aai.org
Although the role of NF-κB in the pathogenesis of sepsis and septic shock has been
extensively studied, little is known about the causative contribution of endothelial-intrinsic …

Nitric oxide: an inhibitor of NF-κB/Rel system in glial cells

M Colasanti, T Persichini - Brain research bulletin, 2000 - Elsevier
Nitric oxide (NO) has been reported to regulate NF-κB, one of the best-characterized
transcription factors playing important roles in many cellular responses to a large variety of …

Flavones and polyphenols inhibit the NO pathway during apoptosis of leukemia B-cells

C Quiney, D Dauzonne, C Kern, JD Fourneron… - Leukemia research, 2004 - Elsevier
We recently reported that resveratrol, a grape-derived polyphenol, in vitro induces the
apoptosis of leukemic B-cells and simultaneously inhibits the production of endogenous …

Cross-talk between constitutive and inducible NO synthase: an update

T Persichini, O Cantoni, H Suzuki… - Antioxidants & redox …, 2006 - liebertpub.com
Inducible nitric oxide synthase (iNOS) is expressed upon exposure of some cell types to
bacterial lipopolysaccharides (LPS) and/or a variety of proinflammatory cytokines. The …