With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

Background: Biological aging may be a robust biomarker of dementia or cognitive
performance. This systematic review synthesized the evidence for an association between …

The geroscience hypothesis proposes that therapy to slow or reverse molecular changes
that occur with aging can delay or prevent multiple chronic diseases and extend healthy …

Slower epigenetic aging is associated with exposure to green space (greenness); however,
the longitudinal relationship has not been well studied, particularly in minority groups. We …

DNA methylation-based (DNAm) measures of biological aging associate with increased risk
of morbidity and mortality, but their links with cognitive decline are less established. This …

According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

Abstract Introduction Native American communities suffer disproportionately from elevated
metal exposures and increased risk for cardiovascular diseases and diabetes. DNA …

Stressful life events have been linked to declining health, and inflammation has been
proposed as a physiological mechanism that might explain this association. Using 828 …

Alzheimer disease (AD) is a common neurodegenerative disease with a late onset. It is
critical to identify novel blood-based DNA methylation biomarkers to better understand the …