Cerebrovascular diseases are a leading cause of death and neurologic disability. Further understanding of disease mechanisms and therapeutic strategies requires a deeper …
J Ren, N Wang, P Guo, Y Fan, F Lin, J Wu - Lab on a Chip, 2022 - pubs.rsc.org
Cell migration is crucial for many biological processes, including normal development, immune response, and tissue homeostasis and many pathological processes such as …
L von Chamier, RF Laine, J Jukkala, C Spahn… - Nature …, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can outperform conventional image processing pipelines. Despite the enthusiasm and …
S Pandey, K Shen, SH Lee, YAA Shen, Y Wang… - Cell reports, 2022 - cell.com
Oligodendrocyte dysfunction has been implicated in the pathogenesis of neurodegenerative diseases, so understanding oligodendrocyte activation states would shed light on disease …
The human brain is subdivided into distinct anatomical structures, including the neocortex, which in turn encompasses dozens of distinct specialized cortical areas. Early …
Neoadjuvant chemotherapy (NAC) prior to surgery and immune checkpoint therapy (ICT) have revolutionized bladder cancer management. However, stratification of patients that …
M Jan, A Spangaro, M Lenartowicz… - BioEssays, 2024 - Wiley Online Library
Bioimage analysis plays a critical role in extracting information from biological images, enabling deeper insights into cellular structures and processes. The integration of machine …
K Ulicna, G Vallardi, G Charras… - Frontiers in Computer …, 2021 - frontiersin.org
Single-cell methods are beginning to reveal the intrinsic heterogeneity in cell populations, arising from the interplay of deterministic and stochastic processes. However, it remains …
Ubiquitination is a post-translational modification initiated by the E1 enzyme UBA1, which transfers ubiquitin to~ 35 E2 ubiquitin-conjugating enzymes. While UBA1 loss is cell lethal, it …