[HTML][HTML] Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations–A review

M Kumar, AR Hilles, SH Almurisi, A Bhatia, S Mahmood - JCIS Open, 2023 - Elsevier
The lung is an attractive target for drug delivery because of the ease of non-invasive
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Physicochemical properties affecting the fate of nanoparticles in pulmonary drug delivery

Q Liu, J Guan, L Qin, X Zhang, S Mao - Drug discovery today, 2020 - Elsevier
Highlights•Clearance routes of nanoparticles in the lung are presented.•Factors influencing
nanoparticle transaction are discussed.•Physicochemical properties of the nanoparticles …

Overcoming hurdles in nanoparticle clinical translation: The influence of experimental design and surface modification

JW Shreffler, JE Pullan, KM Dailey, S Mallik… - International journal of …, 2019 - mdpi.com
Nanoparticles are becoming an increasingly popular tool for biomedical imaging and drug
delivery. While the prevalence of nanoparticle drug-delivery systems reported in the …

Pharmacokinetics of inhaled nanotherapeutics for pulmonary delivery

AM Shen, T Minko - Journal of Controlled Release, 2020 - Elsevier
Pulmonary delivery of lipid-based nanotherapeutics by inhalation presents an
advantageous alternative to oral and intravenous routes of administration that avoids …

Recent advances in epsilon-poly-L-lysine and L-lysine-based dendrimer synthesis, modification, and biomedical applications

S Chen, S Huang, Y Li, C Zhou - Frontiers in Chemistry, 2021 - frontiersin.org
With the advantages in biocompatibility, antimicrobial ability, and comparative facile
synthesis technology, poly-L-lysine (PLL) has received considerable attention in recent …

Highly branched polymers based on poly (amino acid) s for biomedical application

M Thompson, C Scholz - Nanomaterials, 2021 - mdpi.com
Polymers consisting of amino acid building blocks continue to receive consideration for
biomedical applications. Since poly (amino acid) s are built from natural amino acids, the …

Biomedical nanomaterials for immunological applications: ongoing research and clinical trials

V Lenders, X Koutsoumpou, A Sargsian… - Nanoscale …, 2020 - pubs.rsc.org
Research efforts on nanomaterial-based therapies for the treatment of autoimmune diseases
and cancer have spiked and have made rapid progress over the past years. Nanomedicine …

Advanced delivery systems based on lysine or lysine polymers

S Manouchehri, P Zarrintaj, MR Saeb… - Molecular …, 2021 - ACS Publications
Polylysine and materials that integrate lysine form promising drug delivery platforms. As a
cationic macromolecule, a polylysine polymer electrostatically interacts with cells and is …

Dendrimers for pulmonary delivery: current perspectives and future challenges

P Mehta, S Kadam, A Pawar, C Bothiraja - New Journal of Chemistry, 2019 - pubs.rsc.org
Dendrimers and dendrimer-based delivery systems are potential biomedicines in the rapidly
growing field of nanomedicine. At present, dendrimers are drawing attention in the scientific …