Bacterial infections represent a significant health threat globally, and are responsible for the
majority of hospital-acquired infections, leading to extensive mortality and burden on global …

The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

Fluoroquinolones are considered one of the widely utilized antibiotics, specifically, with the
recent development of newer generations such as moxifloxacin, delafloxacin and …

Although drugs currently used for the various types of diseases (eg, antiparasitic, antiviral,
antibacterial, etc.) are effective, they present several undesirable pharmacological and …

Chirality is one of the most widespread properties in nature. After the successful application
of non-optical active carbon dots (CDs) in the fields of detection, imaging, and antibacterial …

Amino acids/peptide conjugated heterocycles represent an important class of therapeutical
agents. Biologically active heterocycles are conjugated with amino acids or peptides to …

In this study, we aimed to synthesize new peptide-substituted cyclotriphosphazenes from a
series of tyrosine-based peptides and dioxyphenyl-substituted spirocyclotriphosphazenes …

Novel, quinolone–fluoroquinolone conjugates 10a–f, 11a–f, 13a–f and 14a–f with amino
acid linkers were synthesized in good yields utilizing benzotriazole chemistry. Antibacterial …