The ten pitfalls of lactate clearance in sepsis

G Hernandez, R Bellomo, J Bakker - Intensive care medicine, 2019 - Springer
Clearance is the removal of a substance from blood, expressed as a volume (milliliters) over
time (minutes). However, changes in lactate levels are the sum of ongoing production and …

Albumin corrected anion gap for predicting in-hospital mortality among intensive care patients with sepsis: a retrospective propensity score matching analysis

T Hu, Z Zhang, Y Jiang - Clinica chimica acta, 2021 - Elsevier
Background The relationship between albumin corrected anion gap (ACAG) and in-hospital
mortality of intensive care sepsis patients is currently inconclusive. Methods The baseline …

Serum anion gap predicts all‐cause mortality in critically ill patients with acute kidney injury: analysis of the MIMIC‐III database

B Cheng, D Li, Y Gong, B Ying, B Wang - Disease markers, 2020 - Wiley Online Library
Background. No epidemiological study has investigated the effect of anion gap (AG) on the
prognosis of critically ill patients with acute kidney injury (AKI). Therefore, we aimed to …

Serum anion gap at admission predicts all-cause mortality in critically ill patients with cerebral infarction: evidence from the MIMIC-III database

X Liu, Y Feng, X Zhu, Y Shi, M Lin, X Song, J Tu… - Biomarkers, 2020 - Taylor & Francis
Background Recent studies reported that serum anion gap could be regarded as a
prognostic biomarker for patients admitted to intensive care units. However, the association …

The association between anion gap and in-hospital mortality of post-cardiac arrest patients: a retrospective study

J Chen, C Dai, Y Yang, Y Wang, R Zeng, B Li, Q Liu - Scientific Reports, 2022 - nature.com
We aimed to determine the association between anion gap and in-hospital mortality in post-
cardiac arrest (CA) patients. Extracted the data of patients diagnosed with CA from MIMIC-IV …

Lactate, bicarbonate and anion gap for evaluation of patients presenting with sepsis to the emergency department: a prospective cohort study

B Mitra, C Roman, KE Charters… - Emergency Medicine …, 2020 - Wiley Online Library
Objective A serum lactate level> 2 mmol/L has been chosen as the preferred cut‐off value
for screening of patients with suspected sepsis. In patients with suspected sepsis presenting …

Association between anion gap and mortality in critically ill patients with cardiogenic shock

T Zhang, J Wang, X Li - International Journal of General Medicine, 2021 - Taylor & Francis
Background No epidemiological study has determined the association between the anion
gap (AG) and all-cause mortality in critically ill patients with cardiogenic shock (CS). This …

Serum anion gap level predicts all-cause mortality in septic patients: A retrospective study based on the MIMIC III database

Y Zhu, Z He, Y Jin, S Zhu, W Xu, B Li… - Journal of Intensive …, 2023 - journals.sagepub.com
Purpose Sepsis is a significant threat in the intensive care unit (ICU) worldwide because it
has high morbidity and mortality rates. Early recognition and diagnosis of sepsis are …

Anion gap reference intervals show instrument dependence and weak correlation with albumin levels

B Pratumvinit, L Lam, N Kongruttanachok… - Clinica Chimica …, 2020 - Elsevier
Background Anion gap (AG) aids the differential diagnosis of acid-base disorders. Its value
has decreased, because of new analytical methods. Our goal was to compare AG reference …

Identifying subpopulations of septic patients: A temporal data-driven approach

A Sharafoddini, JA Dubin, J Lee - Computers in Biology and Medicine, 2021 - Elsevier
Sepsis is one of the deadliest diseases in North America and in spite of the vast amount of
research on this topic there is still uncertainty in the outcome of sepsis treatments. This study …