Bronchopulmonary dysplasia (BPD) is a debilitating disease in premature infants resulting
from lung injury that disrupts alveolar and pulmonary vascular development. Despite the use …

Group B streptococci (GBS) are Gram-positive β-hemolytic bacteria that can cause serious
and life-threatening infections in neonates manifesting as sepsis, pneumonia, meningitis …

Introduction Streptococcus agalactiae (Group B Streptococcus, GBS) is a leading pathogen
of neonatal sepsis. The host-pathogen interactions underlying the progression to life …

Siglec-1, also known as Sialoadhesin (Sn) and CD169 is highly conserved among
vertebrates and with 17 immunoglobulin-like domains is Siglec-1 the largest member of the …

The Siglecs family is a group of type I sialic acid-binding immunoglobulin-like receptors that
regulate cellular signaling by recognizing sialic acid epitopes. Siglecs are predominantly …

Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a predominant
pathogen of neonatal sepsis, commonly associated with early-onset neonatal sepsis. GBS …

Immaturity of alveolar macrophages (AMs) around birth contributes to the susceptibility of
newborns to lung disease. However, the molecular features differentiating neonatal and …

The mammalian Siglec receptor sialoadhesin (Siglec1, CD169) confers innate immunity
against the encapsulated pathogen group B Streptococcus (GBS). Newborn lung …

Alveolar macrophages are pivotal components of the lung's innate immune defense against
respiratory virus infections. Their multifaceted role spans from viral clearance to modulation …

Objective This study aimed to explore the effects of Parkin (Prkn) knockout in a juvenile
mouse model of asthma. Methods Prkn knockout (KO) and wild type (WT) mice were utilized …