Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation

SR Khan, BK Canales… - Nature Reviews …, 2021 - nature.com
Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …

The role of exosomes and exosomal microRNA in cardiovascular disease

D Zheng, M Huo, B Li, W Wang, H Piao… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …

[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets

C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are nanosized lipid vesicles originating from the endosomal system that carry
many macromolecules from their parental cells and play important roles in intercellular …

Biomarkers of vascular calcification in serum

S Roumeliotis, A Roumeliotis, E Dounousi… - Advances in clinical …, 2020 - Elsevier
Over the last decades, the association between vascular calcification (VC) and all-
cause/cardiovascular mortality, especially in patients with high atherogenic status, such as …

AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization

J Yang, T Pei, G Su, P Duan, X Liu - Frontiers in Cell and …, 2023 - frontiersin.org
The mineralization of the extracellular matrix (ECM) is an essential and crucial process for
physiological bone formation and pathological calcification. The abnormal function of ECM …

Exosomal STAT1 derived from high phosphorus‑stimulated vascular endothelial cells induces vascular smooth muscle cell calcification via the Wnt/β‑catenin signaling …

Z Qin, Y Li, J Li, L Jiang, Z Zhang… - International …, 2022 - spandidos-publications.com
Vascular calcification is commonly observed in chronic kidney disease. The mechanism of
how the calcification signal from endothelial cells is transmitted to vascular smooth muscle …

The role of mitochondria in vascular calcification

P Wang, N Zhang, B Wu, S Wu, Y Zhang… - Journal of Translational …, 2020 - degruyter.com
Vascular calcification (VC) was defined as the ectopic deposition of calcium–phosphorus
complexes on the blood vessel walls. It was a process involving multiple factors and …

Exosomal miRNA analysis of aqueous humour of diabetes and cataract patients

C Gao, F Fan, X Liu, J Yang, X Zhou, H Mei… - Current Eye …, 2021 - Taylor & Francis
Background The mechanism of diabetes and cataracts is complicated. Considering our
increasing acknowledge of exosomes, exosomal miRNAs isolated from aqueous humour …

Ferritin in kidney and vascular related diseases: novel roles for an old player

J Balla, G Balla, A Zarjou - Pharmaceuticals, 2019 - mdpi.com
Iron is at the forefront of a number of pivotal biological processes due to its ability to readily
accept and donate electrons. However, this property may also catalyze the generation of …

The emerging role of mesenchymal stem cells in vascular calcification

C Xie, L Ouyang, J Chen, H Zhang, P Luo… - Stem cells …, 2019 - Wiley Online Library
Vascular calcification (VC), characterized by hydroxyapatite crystal depositing in the vessel
wall, is a common pathological condition shared by many chronic diseases and an …