The potential role of m6A reader YTHDF1 as diagnostic biomarker and the signaling pathways in tumorigenesis and metastasis in pan-cancer
Y Zhu, J Li, H Yang, X Yang, Y Zhang, X Yu, Y Li… - Cell Death …, 2023 - nature.com
Abstract m6A is an important RNA methylation in progression of various human cancers. As
the m6A reader protein, YTHDF1 is reported to accelerate m6A-modified mRNAs translation …
the m6A reader protein, YTHDF1 is reported to accelerate m6A-modified mRNAs translation …
The function and clinical implication of YTHDF1 in the human system development and cancer
YTHDF1 is a well-characterized m6A reader protein that is essential for protein translation,
stem cell self-renewal, and embryonic development. YTHDF1 regulates target gene …
stem cell self-renewal, and embryonic development. YTHDF1 regulates target gene …
Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway
J Sun, H Zhou, Z Chen, H Zhang, Y Cao, X Yao… - Journal of Translational …, 2023 - Springer
Background Denervation-induced muscle atrophy is complex disease involving multiple
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
Epigenetic control of skeletal muscle atrophy
W Liang, F Xu, L Li, C Peng, H Sun, J Qiu… - Cellular & Molecular …, 2024 - Springer
Skeletal muscular atrophy is a complex disease involving a large number of gene
expression regulatory networks and various biological processes. Despite extensive …
expression regulatory networks and various biological processes. Despite extensive …
Exercise promotes skeletal muscle growth in adolescents via modulating Mettl3-mediated m6A methylation of MyoD in muscle satellite cells
S Feng, H Zhou, X Lin, S Zhu, H Chen, H Zhou… - Cellular & Molecular …, 2024 - Springer
Exercise exerts positive impacts on skeletal muscle health and homeostasis. Emerging
evidence suggests that m6A methylation is involved in various physiological processes …
evidence suggests that m6A methylation is involved in various physiological processes …
Ythdf2-mediated STK11 mRNA decay supports myogenesis by inhibiting the AMPK/mTOR pathway
K Deng, Z Liu, X Li, C Ren, Y Fan, J Guo, P Li… - International Journal of …, 2024 - Elsevier
An emerging research focus is the role of m 6 A modifications in mediating the post-
transcriptional regulation of mRNA during mammalian development. Recent evidence …
transcriptional regulation of mRNA during mammalian development. Recent evidence …
[HTML][HTML] METTL16 inhibits differentiation and promotes proliferation and slow myofibers formation in chicken myoblasts
Y Liu, Y Shan, L Pang, Y Tang, M Zhang, Y Tu, G Ji… - Poultry Science, 2024 - Elsevier
ABSTRACT N6-methyladenosine (m6A) plays a crucial regulatory role in muscle growth and
development. In our previous studies, we identified a m6A methyltransferase …
development. In our previous studies, we identified a m6A methyltransferase …
m6A modified pre-miR-503-5P contributes to myogenic differentiation through the activation of mTOR pathway
Y Su, K Deng, Z Liu, Z Zhang, Z Liu, Z Huang… - International Journal of …, 2025 - Elsevier
The post-transcriptional regulation of epigenetic modification is a hot topic in skeletal muscle
development research. Both m6A modifications and miRNAs have been well-established as …
development research. Both m6A modifications and miRNAs have been well-established as …
[HTML][HTML] Regulatory role of m6A epitranscriptomic modifications in normal development and congenital malformations during embryogenesis
Y Yao, P Liu, Y Li, W Wang, H Jia, Y Bai, Z Yuan… - Biomedicine & …, 2024 - Elsevier
The discovery of N6-methyladenosine (m 6 A) methylation and its role in translation has led
to the emergence of a new field of research. Despite accumulating evidence suggesting that …
to the emergence of a new field of research. Despite accumulating evidence suggesting that …
RNA reading protein YTHDF2 mediates Benzo (k) fluoranthene induced male reproductive injury by regulating the stability of BCL2
Y Li, D Wang, H Chen, Y Zeng, N Wang, Y Shi, J Li… - Environmental …, 2024 - Elsevier
Abstract Benzo (k) fluoranthene (BkF) has adverse effects on male reproduction, but its
specific mechanism of action is still unclear. This study focused on the role of RNA reading …
specific mechanism of action is still unclear. This study focused on the role of RNA reading …