Dye‐decolorizing peroxidases (DyP) were originally discovered in fungi for their ability to
decolorize several different industrial dyes. DyPs catalyze the oxidation of a variety of …

The selective hydroxylation of benzene to phenol, without the formation of side products
resulting from overoxidation, is catalyzed by cytochrome P450BM3 with the assistance of …

Bioconjugation, defined as chemical modification of biomolecules, is widely employed in
biological and biophysical studies. It can expand functional diversity and enable …

The direct syntheses of ureas, oxamides, 2‐oxazolidinones, and benzoxazolones by the
oxidative carbonylation of amines, β‐amino alcohols, and 2‐aminophenols allows us to …

Despite its importance and all the considerable efforts made, the progress in drug discovery
is limited. One main reason for this is the partly questionable data quality. Models relating …

The CYP106A subfamily hydroxylates steroids, diterpenes, and triterpenes in a
regioselective and stereoselective manner, which is a challenging task for synthetic …

Bacteriophage research is gaining more importance due to increasing antibiotic resistance.
However, for treatment with bacteriophages, diagnostics have to be improved …

Human aromatase (CYP19A1) is a steroidogenic cytochrome P450 converting androgens
into estrogens. No ligand-free crystal structure of the enzyme is available to date. The crystal …

Pharmacogenomics is a powerful tool to prevent adverse reactions caused by different
response of individuals to drug administration. Single nucleotide polymorphisms (SNPs) …

Docking simulations and experimental data indicate that 22-(N-(7-nitrobenz-2-oxa-1, 3-
diazol-4-yl) amino)-23, 24-bisnor-5-cholen-3β-ol (22-NBD-cholesterol), a common …