The connexin gene family is the most prevalent gene that contributes to hearing loss.
Connexins 26 and 30, encoded by GJB2 and GJB6, respectively, are the most abundantly …

Recent whole exome sequencing studies in humans have provided novel insight into the
importance of the ephrinB2-EphB4-RASA1 signaling axis in cerebrovascular development …

Haploinsufficient mutation in arginine and glutamine-rich protein 1 (Arglu1), a newly
identified pre-mRNA splicing regulator, may be linked to neural developmental disorders …

Eph receptors, comprising the largest family of receptor tyrosine kinases (RTKs), exert
profound influence on diverse biological processes and pathological conditions such as …

In the cochlea, connexin 26 (Cx26) and connexin 30 (Cx30) co‐assemble into two types of
homomeric and heteromeric gap junctions between adjacent non‐sensory epithelial cells …

Aerobic exercise is well known to promote neuroplasticity and hippocampal memory. In the
developing brain, early-life exercise (ELE) can lead to persistent improvements in …

The ephrin receptors (EphRs) are the largest family of receptor tyrosine kinases (RTKs) that
are abundantly expressed in the developing brain and play important roles at different …

In mammals, the functional development of the cochlea requires the tight regulation of
multiple molecules and signalling pathways including fibroblast growth factors, bone …

Chromosome 13q deletions encompassing EFNB2, which encodes the transmembrane
protein ephrin-B2, are likely to cause syndromic forms of sensorineural hearing loss of …

EphrinB2, a membrane-tethered ligand preferentially binding to its receptor EphB4, is
ubiquitously expressed in all mammals. Through the particular bidirectional signaling …