Radioimmunotherapy: from current clinical success to future industrial breakthrough?

F Kraeber-Bodéré, J Barbet… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Radioimmunotherapy is a targeted molecular therapy that bears on radiobiologic and
immunologic processes, without crossresistance with other anticancer cytotoxic drugs. Since …

Therapeutic immunoconjugates. Which cytotoxic payload: chemotherapeutic drug (ADC) or Radionuclide (ARC)?

JF Chatal, F Kraeber-Bodéré… - Current Cancer …, 2016 - ingentaconnect.com
Over the last decade, Antibody Drug Conjugates (ADCs) have gained a great success due
to their documented clinical efficacy and manageable toxicity. Generally the word “drug” is …

[PDF][PDF] Phase I dose− escalation trial of 225Ac− J591 in patients with metastatic castration− resistant prostate cancer

ST Tagawa - cdn.clinicaltrials.gov
Accrual Period: 3 years (approximately 1− 2 patients per month). Study Design: Phase I
dose escalation study with 225Ac− J591 using single dose regimen will be performed in …

Prospects for enhancing efficacy of Radioimmunotherapy

C Bailly, C Bodet-Milin, F Guérard, C Rousseau… - … to Ibritumomab in …, 2018 - Springer
Radioimmunotherapy has been in use for more than 20 years and has progressed
significantly since its efficacy has first been demonstrated in hematology. Yet it still has …

[PDF][PDF] Theranostic radioimmunotherapy (RIT) combined with immunotherapy: the best way to go

JF Chatal - Med Res Innov, 2017 - siriusstore.com
Some quite promising results have been also obtained in solid tumors despite their relative
radioresistance. For treatment of metastatic cancers, single-injection RIT is not realistic for a …

Le cancer de prostate métastatique. Une cible: le PSMA–un traitement: la radioimmunothérapie

C Rousseau, M Le Thiec, V Fleury, D Rusu, A Denis… - Médecine Nucléaire, 2017 - Elsevier
Résumé Le cancer de la prostate métastatique n'est que sensible transitoirement à la
chimiothérapie actuelle. La thérapie par des anticorps monoclonaux radiomarqués qui cible …