Inflammation and liver cancer: molecular mechanisms and therapeutic targets

YM Yang, SY Kim, E Seki - Seminars in liver disease, 2019 - thieme-connect.com
Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …

Hepatocellular carcinoma: etiology and current and future drugs

A Jindal, A Thadi, K Shailubhai - Journal of clinical and experimental …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is swiftly increasing in prevalence globally with a high
mortality rate. The progression of HCC in patients is induced with advanced fibrosis, mainly …

Molecular mechanisms of viral oncogenesis in humans

NA Krump, J You - Nature Reviews Microbiology, 2018 - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …

Etiology of hepatocellular carcinoma: special focus on fatty liver disease

D Suresh, AN Srinivas, DP Kumar - Frontiers in Oncology, 2020 - frontiersin.org
Hepatocellular Carcinoma (HCC) is a highly aggressive cancer with mortality running
parallel to its incidence and has limited therapeutic options. Chronic liver inflammation and …

Early occurrence and recurrence of hepatocellular carcinoma in HCV-related cirrhosis treated with direct-acting antivirals

F Conti, F Buonfiglioli, A Scuteri, C Crespi, L Bolondi… - Journal of …, 2016 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) represents a serious complication of
HCV-related cirrhosis. New direct-acting antivirals (DAA) cure HCV infection in over 90% of …

Hepatocellular carcinoma: a narrative review on current knowledge and future prospects

B Alawyia, C Constantinou - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement Hepatocellular carcinoma is the fourth leading cause of cancer-related
deaths worldwide and its associated mortality rate is expected to rise within the next decade …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

[HTML][HTML] Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular …

HHM Ng, RY Lee, S Goh, ISY Tay, X Lim… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Methods Clinically annotated samples from 49 patients with advanced HCC treated with ICB
were analyzed for CD38 expression using immunohistochemistry (IHC), multiplex …

The potential role of the microbiota in prostate cancer pathogenesis and treatment

N Pernigoni, C Guo, L Gallagher, W Yuan… - Nature Reviews …, 2023 - nature.com
The human body hosts a complex and dynamic population of trillions of microorganisms—
the microbiota—which influences the body in homeostasis and disease, including cancer …