Research Advances on Health Effects of Edible Artemisia Species and Some Sesquiterpene Lactones Constituents

A Trendafilova, LM Moujir, PMC Sousa, AML Seca - Foods, 2020 - mdpi.com
The genus Artemisia, often known collectively as “wormwood”, has aroused great interest in
the scientific community, pharmaceutical and food industries, generating many studies on …

From plant to chemistry: Sources of active opioid antinociceptive principles for medicinal chemistry and drug design

R Turnaturi, S Piana, S Spoto, G Costanzo, L Reina… - Molecules, 2023 - mdpi.com
Pain continues to be an enormous global health challenge, with millions of new untreated or
inadequately treated patients reported annually. With respect to current clinical applications …

Anti-inflammatory, antinociceptive, and antioxidant properties of anacardic acid in experimental models

AL Gomes Junior, MT Islam, LAD Nicolau… - ACS …, 2020 - ACS Publications
Anacardic acid (AA), a compound extracted from cashew nut liquid, exhibits numerous
pharmacological activities. The aim of the current investigation was to assess the anti …

Anti-nociceptive and antioxidant activity of betaine on formalin-and writhing tests induced pain in mice

S Hassanpour, H Rezaei, SM Razavi - Behavioural brain research, 2020 - Elsevier
Pain is a physiological response which is mediated via the central and peripheral nervous
system. Betaine, is a methyl glycine derivative and a commonly used nutrient supplement …

Investigation of the chemical structure and analgesic and anti-inflammatory properties of polysaccharides that constitute the dietary fibers of soursop (Annona muricata …

CL Leivas, TM Cantu-Jungles, BB da Luz… - Food Research …, 2023 - Elsevier
Soursop fruits are widely used in the folk medicine to treat a variety of health conditions.
Once the chemical structure of dietary fibers from fruits is closely related to its biological …

Analgesic effects of fisetin, peimine, astaxanthin, artemisinin, bardoxolone methyl and 740 YP and their influence on opioid analgesia in a mouse model of …

K Ciapała, E Rojewska, K Pawlik… - International Journal of …, 2023 - mdpi.com
Treatment of neuropathic pain remains a challenge for modern medicine due to the
insufficiently understood molecular mechanisms of its development and maintenance. One …

Endogenous opiates and behavior: 2019

RJ Bodnar - Peptides, 2021 - Elsevier
This paper is the forty-second consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Examination of the effects of vitexin and vitexin-loaded solid lipid nanoparticles on neuropathic pain and possible mechanisms of action

H Eken, NB Turkmen, B Senel, R Arslan - Neuropharmacology, 2024 - Elsevier
This research aims to investigate the possible antiallodynic and antihyperalgesic effects of
pure vitexin and vitexin-loaded solid lipid nanoparticles (SLN) on neuropathic pain and the …

Antinociception induced by artemisinin nanocapsule in a model of postoperative pain via spinal TLR4 inhibition

LMS Elisei, TR Moraes, IH Malta, I Charlie-Silva… - …, 2020 - Springer
Artemisinin (ART) was initially described for the control of inflammation and pain. However,
the mechanisms involved with its antinociceptive effect are still poorly understood. Thus, this …

The antimalarial artemisinin is a non-electrophilic agonist of the transient receptor potential ankyrin type 1 receptor-channel

DE Huţanu, G Oprita, D Domocos, T Selescu… - European Journal of …, 2023 - Elsevier
Artemisinin and its derivatives are the main therapeutic drugs against Plasmodium protists,
the causative agents of malaria. While several putative mechanisms of action have been …