Pre-clinical tumor models of primary brain tumors: Challenges and opportunities

F Akter, B Simon, NL de Boer, N Redjal… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Primary brain tumors are a heterogeneous group of malignancies that originate in cells of
the central nervous system. A variety of models tractable for preclinical studies have been …

Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

JK Khalsa, N Cheng, J Keegan, A Chaudry… - Nature …, 2020 - nature.com
Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy
in highly malignant brain-tumors, glioblastomas (GBM), is limited. Here, we generate distinct …

Immune profiling of syngeneic murine and patient GBMs for effective translation of immunotherapies

JK Khalsa, K Shah - Cells, 2021 - mdpi.com
Immunotherapy for brain tumors remains elusive, unlike many other cancer types for which it
is one of the most promising therapeutic options. Recent studies have comprehensively …

Method of treating glioblastoma multiforme

K Shah - US Patent 12,016,882, 2024 - Google Patents
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl) anilino] pyrimidin-4-yl]
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …

[PDF][PDF] BBA-Reviews on Cancer

F Akter, B Simon, NL de Boer, N Redjal, H Wakimoto… - researchgate.net
Primary brain tumors are a heterogeneous group of malignancies that originate in cells of
the central nervous system. A variety of models tractable for preclinical studies have been …

Msc-expressed immunomodulators in combination with car-t for cancer therapy

K Shah - 2019 - Google Patents
WO2019104037A1 - Msc-expressed immunomodulators in combination with car-t for
cancer therapy - Google Patents WO2019104037A1 - Msc-expressed immunomodulators in …

Isı şok protein 10 (HSP10)'un mezenkimal kök hücrelerin immünmodülasyonundaki rolünün araştırılması

A Sarıkaya - 2018 - search.proquest.com
Bu tez çalışması kapsamında, Isı şok protein 10 (Hsp10)'un Mezenkimal kök hücrelerin
(MKH) immünomodülasyonundaki rolü araştırıldı. Hücrelerin karakterizasyonu için stromal …