Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques
S Jegaskanda, JT Weinfurter, TC Friedrich… - Journal of …, 2013 - Am Soc Microbiol
Emerging influenza viruses pose a serious risk to global human health. Recent studies in
ferrets, macaques, and humans suggest that seasonal H1N1 (sH1N1) infection provides …
ferrets, macaques, and humans suggest that seasonal H1N1 (sH1N1) infection provides …
The influence of delivery vectors on HIV vaccine efficacy
BO Ondondo - Frontiers in microbiology, 2014 - frontiersin.org
Development of an effective HIV/AIDS vaccine remains a big challenge, largely due to the
enormous HIV diversity which propels immune escape. Thus novel vaccine strategies are …
enormous HIV diversity which propels immune escape. Thus novel vaccine strategies are …
Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques
Y Xu, C Weatherall, M Bailey, S Alcantara… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT T follicular helper (Tfh) cells are a specialized subset of memory CD4+ T cells
that are found exclusively within the germinal centers of secondary lymphoid tissues and are …
that are found exclusively within the germinal centers of secondary lymphoid tissues and are …
Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection
MS Parsons, SB Lloyd, WS Lee… - Science translational …, 2017 - science.org
Broadly neutralizing antibodies (BnAbs) protect macaques from cell-free simian/human
immunodeficiency virus (SHIV) challenge, but their efficacy against cell-associated SHIV is …
immunodeficiency virus (SHIV) challenge, but their efficacy against cell-associated SHIV is …
Induction of potent and long-lived antibody and cellular immune responses in the genitorectal mucosa could be the critical determinant of HIV vaccine efficacy
N Chanzu, B Ondondo - Frontiers in immunology, 2014 - frontiersin.org
The field of HIV prevention has indeed progressed in leaps and bounds, but with major
limitations of the current prevention and treatment options, the world remains desperate for …
limitations of the current prevention and treatment options, the world remains desperate for …
Standard trivalent influenza virus protein vaccination does not prime antibody-dependent cellular cytotoxicity in macaques
S Jegaskanda, TH Amarasena, KL Laurie… - Journal of …, 2013 - Am Soc Microbiol
Yearly vaccination with the trivalent inactivated influenza vaccine (TIV) is recommended,
since current vaccines induce little cross neutralization to divergent influenza strains …
since current vaccines induce little cross neutralization to divergent influenza strains …
[HTML][HTML] Unique IL-13Rα2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8+ T-cell avidity and protective immunity
We have established that mucosal immunization can generate high-avidity human
immunodeficiency virus (HIV)-specific CD8+ T cells compared with systemic immunization …
immunodeficiency virus (HIV)-specific CD8+ T cells compared with systemic immunization …
Epitope‐specific CD4+, but not CD8+, T‐cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection
M Flórido, R Pillay, CM Gillis, Y Xia… - European journal of …, 2015 - Wiley Online Library
Tuberculosis remains a global health problem, in part due to failure of the currently available
vaccine, BCG, to protect adults against pulmonary forms of the disease. We explored the …
vaccine, BCG, to protect adults against pulmonary forms of the disease. We explored the …
Linking pig-tailed macaque major histocompatibility complex class I haplotypes and cytotoxic T lymphocyte escape mutations in simian immunodeficiency virus …
SL Gooneratne, H Alinejad-Rokny, D Ebrahimi… - Journal of …, 2014 - Am Soc Microbiol
The influence of major histocompatibility complex class I (MHC-I) alleles on human
immunodeficiency virus (HIV) diversity in humans has been well characterized at the …
immunodeficiency virus (HIV) diversity in humans has been well characterized at the …
A comparative analysis of HIV-specific mucosal/systemic T cell immunity and avidity following rDNA/rFPV and poxvirus–poxvirus prime boost immunisations
In this study we have firstly compared a range of recombinant DNA poxvirus prime-boost
immunisation strategies and shown that combined intramuscular (im) 2× DNA-HIV/intranasal …
immunisation strategies and shown that combined intramuscular (im) 2× DNA-HIV/intranasal …