Glycans linked to proteins and lipids play key roles in biology; thus, accurate replication of
cellular glycans is crucial for maintaining function following cell division. The fact that …

Glycosyltransferases catalyze glycosidic bond formation using sugar donors containing a
nucleoside phosphate or a lipid phosphate leaving group. Only two structural folds, GT-A …

▪ Abstract Virtually every cell type in metazoan organisms produces heparan sulfate. These
complex polysaccharides provide docking sites for numerous protein ligands and receptors …

Glycosyltransferases are a ubiquitous group of enzymes that catalyse the transfer of a sugar
moiety from an activated sugar donor onto saccharide or non-saccharide acceptors …

Glycosyltransferases (GTs) catalyze the transfer of a sugar moiety from an activated donor
sugar onto saccharide and nonsaccharide acceptors. A sequence-based classification …

Implantation in humans is a complex process that is temporally and spatially restricted. Over
the past decade, using a one-by-one approach, several genes and gene products that may …

The past year has witnessed the expected increase in the number of solved structures of
glycoside hydrolases and glycosyltransferases, and their constitutive modules. These …

Recent cDNA cloning of the glycosyltransferases involved in the synthesis of the sulfated
glycosaminoglycan sidechains of proteoglycans has provided important clues to answering …

Glycosylation is a ubiquitous reaction controlling the bioactivity and storage of plant natural
products. Glycosylation of small molecules is catalyzed by a superfamily of …

Cellular glycome assembly requires the coordinated action of a large number of
glycosyltransferases that catalyse the transfer of a sugar residue from a donor to specific …