Inter-organ crosstalk during development and progression of type 2 diabetes mellitus

G Xourafa, M Korbmacher, M Roden - Nature Reviews Endocrinology, 2024 - nature.com
Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

Neuregulin 4 as a novel adipokine in energy metabolism

Y Liu, M Chen - Frontiers in Physiology, 2023 - frontiersin.org
Adipose tissue has been shown to play a key role in energy metabolism and it has been
shown to regulate metabolic homeostasis through the secretion of adipokines. Neuregulin 4 …

Does C-reactive protein to serum Albumin Ratio correlate with diabEtic nephropathy in patients with Type 2 dIabetes MEllitus? The CARE TIME study

S Bilgin, O Kurtkulagi, BMA Tel, TT Duman… - Primary care …, 2021 - Elsevier
Abstract Aims Diabetic Nephropathy (DN) is a complication of Diabetes Mellitus and is
associated with chronic and low-grade inflammatory burden. Novel inflammatory predictors …

Impact of red cell distribution width and red cell distribution width/albumin ratio on all-cause mortality in patients with type 2 diabetes and foot ulcers: a retrospective …

J Hong, X Hu, W Liu, X Qian, F Jiang, Z Xu… - Cardiovascular …, 2022 - Springer
Background Red blood cell distribution width (RDW) has emerged as a prognostic factor for
mortality in various diseases. Up to now, few studies have focused on the prognostic value …

Serum C-reactive protein to albumin ratio as a reliable marker of diabetic neuropathy in type 2 diabetes mellitus

G Aktas - Biomolecules and biomedicine, 2024 - pmc.ncbi.nlm.nih.gov
In various diseases characterized by inflammation, the C-reactive protein to albumin ratio
(CAR) serves as a marker of inflammation. Type 2 diabetes mellitus (T2DM) is frequently …

Correlation between glycemic variability and diabetic complications: a narrative review

L Huang, Y Pan, K Zhou, H Liu… - International Journal of …, 2023 - Taylor & Francis
Diabetes mellitus is a metabolic disorder with a complex etiology in which glycemic
dynamics are disturbed and the body is unable to maintain the process of glucose …

Low circulating levels of neuregulin 4 as a potential biomarker associated with the severity and prognosis of obesity-related metabolic diseases: a systematic review

K Ziqubu, PV Dludla, SXH Mthembu, B Nkambule… - Adipocyte, 2024 - Taylor & Francis
ABSTRACT Background Neuregulin 4 (Nrg4) is a brown adipose tissue-derived adipokine
that greatly affects systemic metabolism and improves metabolic derangements. Although …

Association between uric acid to HDL cholesterol ratio and diabetic complications in men and postmenopausal women

Y Xuan, W Zhang, Y Wang, B Wang, F Xia… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Aim Previous studies have implicated the uric acid to high-density lipoprotein cholesterol
(HDL-C) ratio (UHR) was associated with type 2 diabetes. However, the association …

The role and mechanisms of microvascular damage in the ischemic myocardium

BH Zhao, A Ruze, L Zhao, QL Li, J Tang… - Cellular and Molecular …, 2023 - Springer
Following myocardial ischemic injury, the most effective clinical intervention is timely
restoration of blood perfusion to ischemic but viable myocardium to reduce irreversible …

Controlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complications

G Aktas, TT Duman, B Atak Tel - Postgraduate Medicine, 2024 - Taylor & Francis
Objectives Type 2 diabetes mellitus (T2DM) and its microvascular complications are
characterized by chronic inflammation. The Controlling Nutritional Status (CONUT) score is …