Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

[HTML][HTML] Single isomer cyclodextrins as chiral selectors in capillary electrophoresis

I Fejős, E Kalydi, M Malanga, G Benkovics… - … of Chromatography A, 2020 - Elsevier
Since decades, cyclodextrins are one of the most powerful selectors in chiral capillary
electrophoresis for the enantioseparation of diverse organic compounds. This review …

[HTML][HTML] Separation of enantiomers and positional isomers of novel psychoactive substances in solid samples by chromatographic and electrophoretic techniques–A …

MG Schmid, JS Hägele - Journal of Chromatography A, 2020 - Elsevier
Abstract Novel Psychoactive Substances (NPS) represent an alternative to established illicit
drugs. They are traded via the internet and exhibit small alterations in their chemical …

Negatively charged cyclodextrins: Synthesis and applications in chiral analysis-A review

C Guo, Y Xiao - Carbohydrate Polymers, 2021 - Elsevier
The negatively charged cyclodextrins (CDs) play an important role in chiral analysis due to
the additional electrostatic effect beyond the host-guest inclusion, especially in …

Determination of the chiral status of different novel psychoactive substance classes by capillary electrophoresis and β‐cyclodextrin derivatives

JS Hägele, EM Hubner, MG Schmid - Chirality, 2020 - Wiley Online Library
Besides the abuse of well‐known illicit drugs, consumers discovered new synthetic
compounds with similar effects but minor alterations in their chemical structure. Originally …

Chiral separation of cathinone derivatives using β‐cyclodextrin‐assisted capillary electrophoresis–Comparison of four different β‐cyclodextrin derivatives used as …

JS Hägele, EM Hubner, MG Schmid - Electrophoresis, 2019 - Wiley Online Library
In the past decade, more than 100 different cathinone derivatives slopped over entire
Europe due to their enormous popularity. Generally, these novel psychoactive substances …

Evaluation of cyclodextrin‐and cyclofructan‐based chiral selectors for the enantioseparation of psychoactive substances in capillary electrophoresis

KA Ioannou, A Christou, IJ Stavrou, MG Schmid… - …, 2022 - Wiley Online Library
During this study, a simple and easy‐to‐prepare electrophoretic method was developed for
the enantioseparation of amphetamine and cathinone derivatives. Different types of β …

Affinity interactions by capillary electrophoresis: binding, separation, and detection

F Yu, Q Zhao, D Zhang, Z Yuan, H Wang - Analytical Chemistry, 2018 - ACS Publications
Affinity interactions between molecules constitute this amazing and mysterious world of
human life on earth. At the level of individuals, affinity interactions are fundamental for the …

Recent advances on chiral mobile phase additives: a critical review

Y Li, XN Jin, Y Cheng, XF Ma, Y Wang - Journal of Analysis and Testing, 2022 - Springer
Chirality is one of the fundamental attributes of nature, which exists in different or even
completely opposite metabolic, toxicological and pharmacological properties in organisms …

Comparative analysis of the full set of methylated β‐cyclodextrins as chiral selectors in capillary electrophoresis

E Varga, G Benkovics, A Darcsi, B Várnai… - …, 2019 - Wiley Online Library
The chiral separation ability of the full library of methylated‐β‐cyclodextrins towards
pharmacologically significant racemic drugs including basic compounds was studied by …