Gastrointestinal involvement in Parkinson's disease: pathophysiology, diagnosis, and management

T Warnecke, KH Schäfer, I Claus, K Del Tredici… - npj Parkinson's …, 2022 - nature.com
Growing evidence suggests an increasing significance for the extent of gastrointestinal tract
(GIT) dysfunction in Parkinson's disease (PD). Most patients suffer from GIT symptoms …

Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

The enteric nervous system and gastrointestinal innervation: integrated local and central control

JB Furness, BP Callaghan, LR Rivera… - … gut-brain axis in health and …, 2014 - Springer
The digestive system is innervated through its connections with the central nervous system
(CNS) and by the enteric nervous system (ENS) within the wall of the gastrointestinal tract …

Enteric nervous system development: A crest cell's journey from neural tube to colon

N Nagy, AM Goldstein - Seminars in cell & developmental biology, 2017 - Elsevier
The enteric nervous system (ENS) is comprised of a network of neurons and glial cells that
are responsible for coordinating many aspects of gastrointestinal (GI) function. These cells …

Immunohistochemical analysis of neuron types in the mouse small intestine

ZD Qu, M Thacker, P Castelucci, M Bagyanszki… - Cell and tissue …, 2008 - Springer
The definition of the nerve cell types of the myenteric plexus of the mouse small intestine has
become important, as more researchers turn to the use of mice with genetic mutations to …

Development of enteric neuron diversity

MM Hao, HM Young - Journal of cellular and molecular …, 2009 - Wiley Online Library
Neuronal diversity in the adult enteric nervous system (ENS)• Developmental appearance
and birthdating of enteric neuron subtypes and glial cells‐Developmental appearance of …

Orexins in the brain-gut axis

AL Kirchgessner - Endocrine reviews, 2002 - academic.oup.com
Orexins (hypocretins) are a novel pair of neuropeptides implicated in the regulation of
energy balances and arousal. Previous reports have indicated that orexins are produced …

Classification of human enteric neurons

A Brehmer - Histochemistry and cell biology, 2021 - Springer
Major advances in our understanding of the functional heterogeneity of enteric neurons are
driven by the application of newly developed, innovative methods. In contrast to this …

[HTML][HTML] S100B protein in the gut: the evidence for enteroglial-sustained intestinal inflammation

C Cirillo, G Sarnelli, G Esposito, F Turco… - World journal of …, 2011 - ncbi.nlm.nih.gov
Glial cells in the gut represent the morphological and functional equivalent of astrocytes and
microglia in the central nervous system (CNS). In recent years, the role of enteric glial cells …

Animal models for functional gastrointestinal disorders

A Accarie, T Vanuytsel - Frontiers in psychiatry, 2020 - frontiersin.org
Functional gastrointestinal disorders (FGID), such as functional dyspepsia (FD) and irritable
bowel syndrome (IBS) are characterized by chronic abdominal symptoms in the absence of …