[HTML][HTML] Harnessing tissue-derived extracellular vesicles for osteoarthritis theranostics

B Yin, J Ni, CE Witherel, M Yang, JA Burdick, C Wen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

Y Xin, K Li, M Huang, C Liang, D Siemann, L Wu, Y Tan… - Oncogene, 2023 - nature.com
Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

A multilayered mesoporous gold nanoarchitecture for ultraeffective near‐infrared light‐controlled chemo/photothermal therapy for cancer guided by SERS imaging

B Yin, WKH Ho, X Xia, CKW Chan, Q Zhang, YM Ng… - Small, 2023 - Wiley Online Library
Surface‐enhanced Raman scattering (SERS) imaging has emerged as a promising tool for
guided cancer diagnosis and synergistic therapies, such as combined chemotherapy and …

Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling

SHD Wong, B Yin, Z Li, W Yuan, Q Zhang, X Xie… - Science …, 2023 - science.org
Biophysical cues of rigid tumor matrix play a critical role in cancer cell malignancy. We report
that stiffly confined cancer cells exhibit robust growth of spheroids in the stiff hydrogel that …

[HTML][HTML] Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging

MJ Ko, S Min, H Hong, W Yoo, J Joo, YS Zhang… - Bioactive Materials, 2024 - Elsevier
Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …

Engineering dynamic and interactive biomaterials using material nanoarchitectonics for modulation of cellular behaviors

X Jia, J Chen, W Lv, H Li, K Ariga - Cell Reports Physical Science, 2023 - cell.com
Biophysical cues of native extracellular matrix (ECM) can affect cellular behavior. Although
static properties of biomaterials have been widely explored, there is a growing interest in …

Dynamic Stimulations with Bioengineered Extracellular Matrix‐Mimicking Hydrogels for Mechano Cell Reprogramming and Therapy

Y Shou, XY Teo, KZ Wu, B Bai, ARK Kumar… - Advanced …, 2023 - Wiley Online Library
Cells interact with their surrounding environment through a combination of static and
dynamic mechanical signals that vary over stimulus types, intensity, space, and time …

Smart skin‐adhesive patches: from design to biomedical applications

SHD Wong, GR Deen, JS Bates, C Maiti… - Advanced Functional …, 2023 - Wiley Online Library
With the advancement of medical and digital technologies, smart skin adhesive patches
have emerged as a key player for complex medical purposes. In particular, skin adhesive …

Magnetic-responsive surface-enhanced Raman scattering platform with tunable hot spot for ultrasensitive virus nucleic acid detection

B Yin, WKH Ho, Q Zhang, C Li, Y Huang… - … Applied Materials & …, 2022 - ACS Publications
Surface-enhanced Raman scattering (SERS)-based biosensors are promising tools for virus
nucleic acid detection. However, it remains challenging for SERS-based biosensors using a …

Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies

M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …