The vascular endothelium is a highly specialized barrier that controls passage of fluids and
migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the Angiotensin
converting enzyme 2 (ACE2) receptor present on the cell surface to enter cells. Angiotensin …

Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease leading to
progressive demyelination and neuronal loss, with extensive neurological symptoms. As …

At the moment, anaplastic changes within the brain are challenging due to the complexity of
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …

Background Endothelial hyperpermeability is associated with sepsis and acute respiratory
distress syndrome (ARDS). The identification of molecular pathways involved in barrier …

Neutrophil infiltration and papillary vessel dilation are hallmarks of the initiation phase of
psoriatic lesions. However, how neutrophils aggravate psoriasis development during …

We have shown that both reactive oxygen species (ROS) and paxillin tyrosine
phosphorylation regulate LPS-induced human lung endothelial permeability. Mitochondrial …

Thrombosis, characterized by blood clot formation within vessels, poses a significant
medical challenge. Despite extensive research, the development of effective thrombosis …

Endothelial dysfunction (ED) is critical in the development and progression of cardiovascular
(CV) disorders, yet effective therapeutic targets for ED remain elusive due to limited …

Metastasis-associated processes are the predominant instigator of fatalities linked to cancer,
wherein the pivotal role of circulating tumor cells lies in the resurgence of malignant growth …