[HTML][HTML] SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Quercetin and its derivates as antiviral potentials: A comprehensive review

A Di Petrillo, G Orrù, A Fais… - Phytotherapy Research, 2022 - Wiley Online Library
Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant,
antiviral, antimicrobial, and antiinflammatory properties. Several studies highlight the …

Obesity and diabetes as high‐risk factors for severe coronavirus disease 2019 (Covid‐19)

Y Zhou, J Chi, W Lv, Y Wang - Diabetes/metabolism research …, 2021 - Wiley Online Library
The outbreak of the coronavirus disease 2019 (Covid‐19) has become an evolving
worldwide health crisis. With the rising prevalence of obesity and diabetes has come an …

Coronavirus disease 2019: What we know?

F He, Y Deng, W Li - Journal of medical virology, 2020 - Wiley Online Library
In late December 2019, a cluster of unexplained pneumonia cases has been reported in
Wuhan, China. A few days later, the causative agent of this mysterious pneumonia was …

[HTML][HTML] Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

R Bussani, E Schneider, L Zentilin, C Collesi, H Ali… - …, 2020 - thelancet.com
Background COVID-19 is a deadly pulmonary disease with peculiar characteristics, which
include variable clinical course and thrombophilia. A thorough understanding of the …

[HTML][HTML] Comorbid chronic diseases are strongly correlated with disease severity among COVID-19 patients: a systematic review and meta-analysis

H Liu, S Chen, M Liu, H Nie, H Lu - Aging and disease, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and
mortality worldwide since December 2019. In order to explore the effects of comorbid …

Postmortem examination of patients with COVID-19

T Schaller, K Hirschbühl, K Burkhardt, G Braun… - Jama, 2020 - jamanetwork.com
Methods| Between April 4 and April 19, 2020, we conducted serial postmortem examinations
in patients with proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

N Iwata-Yoshikawa, T Okamura, Y Shimizu… - Journal of …, 2019 - Am Soc Microbiol
Transmembrane serine protease TMPRSS2 activates the spike protein of highly pathogenic
human coronaviruses such as severe acute respiratory syndrome-related coronavirus …

Coagulation abnormalities and thrombosis in patients infected with SARS-CoV-2 and other pandemic viruses

N Mackman, S Antoniak, AS Wolberg… - … , and vascular biology, 2020 - Am Heart Assoc
The world is amid a pandemic caused by severe acute respiratory syndrome-coronavirus 2.
Severe acute respiratory syndrome-coronavirus causes serious respiratory tract infections …

[HTML][HTML] Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

XH Yao, ZC He, TY Li, HR Zhang, Y Wang, H Mou… - Cell research, 2020 - nature.com
SARS-CoV-2, a novel coronavirus and causing COVID-19, has given rise to a worldwide
pandemic. 1, 2 So far, tens of thousands of COVID-19 patients have been clinically cured …