The therapeutic efficacy of drugs is dependent upon the ability of a drug to reach its target,
and drug penetration into tumors is limited by abnormal vasculature and high interstitial …

Drug delivery scaffolds are smart alternatives to conventional formulations and allow for
controlled spatiotemporal releases of active compounds. In several fields of human health …

Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free
macromolecular therapeutics) are a group of biologically active compounds that are …

Ferroptosis is a form of non-apoptotic iron induced cell death mechanism implicated in
neurodegeneration, yet can be ameliorated with potent radical scavengers such as …

Non-covalent imprinting polymerization was adopted to fabricate a novel molecularly
imprinted polymer (MIP) for the targeted delivery of Irinotecan. The optimized condition to …

With the advancement of medical technology, the previous biomedical material platforms
have been unable to meet the increasingly diverse application requirements, and the …

A dynamic thermo-responsive drug delivery concept using poly (2-oxazoline) copolymers
conjugated with a hydrophobic drug is presented. The novel strategy entails the synthesis of …

Dye-functionalized polymers have been extensively studied to understand polymer chain
dynamics, intra or inter-molecular association and conformational changes as well as in …

Solid tumors are composed of a complex organ-like structure, comprising tumor, immune
and stromal cells, extracellular matrix (ECM), and blood vessels. Tumor microenvironments …