Astrocytes are a population of cells with distinctive morphological and functional
characteristics that differ within specific areas of the brain. Postnatally, astrocyte progenitors …

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

Bioactive compounds from medicinal plants with anti-inflammatory and immunosuppressive
effects have been emerging as important sources of drugs for the treatment of inflammatory …

In the past decades, triptolide has attracted considerable interests in the organic and
medicinal chemistry society owing to its intriguing structure features and promising multiple …

Abstract Alzheimer's disease (AD), a persistent neurological dysfunction, has an increasing
prevalence with the aging of the world and seriously threatens the health of the elderly …

Abstract Introduction DL-3-n-butylphthalide (NBP) and edaravone dexborneol (Eda-Dex) are
two promising reagents for stroke treatment. However, the impacts of NBP and Eda-Dex on …

Neurological diseases are complex diseases affecting the brain and spinal cord, with
numerous etiologies and pathogenesis not yet fully elucidated. Tripterygium wilfordii Hook …

One of the biggest challenges in drug development for Alzheimer's disease (AD) is how to
effectively remove deposits of amyloid-beta (Aβ). Recently, the relationship between …

Previous studies have shown that sirtuin 1 (SIRT1) reduces the production of neuronal
amyloid beta (Aβ) and inhibits the inflammatory response of glial cells, thereby generating a …

Triptolide, a complex triepoxide diterpene natural product, has attracted considerable
interest in the medicinal society due to its multiple biological activities. However, poor water …