Recent progress of microfluidic technology for pharmaceutical analysis

X Jia, X Yang, G Luo, Q Liang - Journal of Pharmaceutical and Biomedical …, 2022 - Elsevier
In recent years, the progress of microfluidic technology has provided new tools for
pharmaceutical analysis and the proposal of pharm-lab-on-a-chip is appealing for its great …

A review of optical imaging technologies for microfluidics

P Zhou, H He, H Ma, S Wang, S Hu - Micromachines, 2022 - mdpi.com
Microfluidics can precisely control and manipulate micro-scale fluids, and are also known as
lab-on-a-chip or micro total analysis systems. Microfluidics have huge application potential …

Optofluidic imaging meets deep learning: from merging to emerging

DMD Siu, KCM Lee, BMF Chung, JSJ Wong, G Zheng… - Lab on a Chip, 2023 - pubs.rsc.org
Propelled by the striking advances in optical microscopy and deep learning (DL), the role of
imaging in lab-on-a-chip has dramatically been transformed from a silo inspection tool to a …

Three-dimensional imaging on a chip using optofluidics light-sheet fluorescence microscopy

EJ Vargas-Ordaz, S Gorelick, HM York, B Liu, ML Halls… - Lab on a Chip, 2021 - pubs.rsc.org
Volumetric, sub-micron to micron level resolution imaging is necessary to assay phenotypes
or characteristics at the sub-cellular/organelle scale. However, three-dimensional …

Quantifying DNA damage following light sheet and confocal imaging of the mammalian embryo

DJX Chow, EP Schartner, S Corsetti, A Upadhya… - Scientific Reports, 2024 - nature.com
Embryo quality assessment by optical imaging is increasing in popularity. Among available
optical techniques, light sheet microscopy has emerged as a superior alternative to confocal …

Large-scale high-throughput 3D culture, imaging, and analysis of cell spheroids using microchip-enhanced light-sheet microscopy

T Zhu, J Nie, T Yu, D Zhu, Y Huang, Z Chen… - Biomedical Optics …, 2023 - opg.optica.org
Light sheet microscopy combined with a microchip is an emerging tool in biomedical
research that notably improves efficiency. However, microchip-enhanced light-sheet …

Fly Me to the Micron: Microtechnologies for Drosophila Research

UM Sonmez, N Frey, PR LeDuc… - Annual Review of …, 2024 - annualreviews.org
Multicellular model organisms, such as Drosophila melanogaster (fruit fly), are frequently
used in a myriad of biological research studies due to their biological significance and …

A Review of Single‐Cell Pose Adjustment and Puncture

X Guo, Y Zhang, D Jin, M Zhou - Advanced Intelligent Systems, 2022 - Wiley Online Library
Single‐cell manipulation technology is an essential method of cell research, with wide
applications in biological engineering, medical engineering, agricultural engineering, and …

Structured-light-sheet imaging in an integrated optofluidic platform

P Paiè, G Calisesi, A Candeo, A Comi, F Sala… - Lab on a Chip, 2024 - pubs.rsc.org
Heterogeneity investigation at the single-cell level reveals morphological and phenotypic
characteristics in cell populations. In clinical research, heterogeneity has important …

Microscopic imaging methods for organ-on-a-chip platforms

BC Buchanan, JY Yoon - Micromachines, 2022 - mdpi.com
Microscopic imaging is essential and the most popular method for in situ monitoring and
evaluating the outcome of various organ-on-a-chip (OOC) platforms, including the number …