Pd-catalyzed cross-coupling reactions that form C–N bonds have become useful methods to
synthesize anilines and aniline derivatives, an important class of compounds throughout …

Aurora kinase belongs to serine/threonine kinase family which controls cell division.
Therapeutic inhibition of Aurora kinase showed great promise as probable anticancer …

Pyrazole has been the topic of interest for thousands of researchers across the world
because of its wide spectrum pharmacological activities. Various structural modifications of …

The fusion of pyrazole scaffold with other skeletons creates a class of attractive molecules,
demonstrating significant biological and chemical potentiality in the development of …

The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …

In this review we report the recent advances in bioactive system containing pyrazole fused
with a five membered heterocycle, covering the time span of the last decade. All of them are …

C–N cross-coupling bond formation reactions have become valuable approaches to
synthesizing anilines and their derivatives, known as important chemical compounds …

New pyrazole derivatives were designed and synthesized as potential protein kinase
inhibitors in the view to develop specific antitumor therapies. The structures of the …

A novel series of coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes (4a–o)
were synthesized via an efficient, one-pot multicomponent approach involving 3-(2 …

The aim of this review is to highlight the advances in the field of heme oxygenase-1 (HO-1)
inhibitors over the past years, particularly from a medicinal chemistry point of view; …