Targeted protein degradation, using bifunctional small molecules (Protacs) to remove
specific proteins from within cells, has emerged as a novel drug discovery strategy with the …

Highlights•Nanocrystals are nanosized drug particles produced in the form of
nanosuspensions.•Nanocrystals are an industrially feasible formulation for poorly soluble …

In this study, encapsulation strategy of curcumin was employed by fabricating protein-based
composite nanoparticles with hydrophilic whey protein isolate (WPI) and hydrophobic zein …

Nanoparticles made from natural proteins and polysaccharides are green, biodegradable,
and sustainable. In this study, soybean protein isolate (SPI) and soybean soluble …

Polymeric biomaterials have found widespread applications in nanomedicine, and poly
(lactide-co-glycolide),(PLGA) in particular has been successfully implemented in numerous …

Curcumin is a natural antioxidant with health benefits such as diabetes prevention.
Curcumin is poorly soluble in water and sensitive to oxidation, preventing its absorption …

There is great interest in developing colloidal delivery systems to enhance the water
solubility and oral bioavailability of curcumin, which is a hydrophobic nutraceutical claimed …

Curcumin is a bioactive phytochemical that can be utilized as a nutraceutical or
pharmaceutical in functional foods, supplements, and medicines. However, the application …

Soluble pea protein isolate-curcumin nanoparticles were successfully prepared at a novel
pH combination, with encapsulation efficiency and drug loading amount of 95.69±1.63 …

Nanoparticles are frequently designed to improve the pharmacokinetics profiles and tissue
distribution of small molecules to prolong their systemic circulation, target specific tissue, or …