Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …
medicines that directly reprogramme the central dogma of biology to prevent and treat …
Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
Unlocking the promise of mRNA therapeutics
E Rohner, R Yang, KS Foo, A Goedel… - Nature biotechnology, 2022 - nature.com
The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19)
has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical …
has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical …
The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …
cancer treatment, and the research and development of nanoparticles for drug delivery are …
Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
Biosystem‐inspired engineering of nanozymes for biomedical applications
L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Stealth and pseudo-stealth nanocarriers
The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …
applications through improving the pharmacokinetics such as blood circulation …