Nanocarriers-mediated drug delivery systems for anticancer agents: an overview and perspectives

Z Edis, J Wang, MK Waqas, M Ijaz… - International journal of …, 2021 - Taylor & Francis
Nanotechnology has been actively integrated as drug carriers over the last few years to treat
various cancers. The main hurdle in the clinical management of cancer is the development …

Current trends and challenges in cancer management and therapy using designer nanomaterials

PN Navya, A Kaphle, SP Srinivas, SK Bhargava… - Nano convergence, 2019 - Springer
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

Tumor targeting via EPR: Strategies to enhance patient responses

SK Golombek, JN May, B Theek, L Appold… - Advanced drug delivery …, 2018 - Elsevier
The tumor accumulation of nanomedicines relies on the enhanced permeability and
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …

Applications of patient-derived tumor xenograft models and tumor organoids

GJ Yoshida - Journal of hematology & oncology, 2020 - Springer
Patient-derived tumor xenografts (PDXs), in which tumor fragments surgically dissected from
cancer patients are directly transplanted into immunodeficient mice, have emerged as a …

Recent advances in functionalized nanoparticles in cancer theranostics

S Siddique, JCL Chow - Nanomaterials, 2022 - mdpi.com
Cancer theranostics is the combination of diagnosis and therapeutic approaches for cancer,
which is essential in personalized cancer treatment. The aims of the theranostics application …

Emerging application of magnetic nanoparticles for breast cancer therapy

TT Dongsar, TS Dongsar, MAS Abourehab… - European Polymer …, 2023 - Elsevier
Breast carcinoma is among the most commonly diagnosed cancer in females, responsible
for 15% of all cancer affiliated mortalities and 23% of all cancer incidence. Based on the …

Magnetic nanoparticles for cancer theranostics: Advances and prospects

X Li, W Li, M Wang, Z Liao - Journal of Controlled Release, 2021 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Nanoparticles have been
broadly studied and emerged as a novel approach in diagnosis and treatment of tumors …

Diagnosis and detection of pancreatic cancer

LC Chu, MG Goggins, EK Fishman - The Cancer Journal, 2017 - journals.lww.com
Computed tomography is the first-line imaging modality for suspected pancreatic cancer.
Magnetic resonance cholangiopancreatography is a second-line modality for suspected …

Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework

K Ni, Z Xu, A Culbert, T Luo, N Guo, K Yang… - Nature biomedical …, 2022 - nature.com
Checkpoint blockade elicits durable responses in immunogenic cancers, but it is largely
ineffective in immunologically 'cold'tumours. Here we report the design, synthesis and …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …