The influence of early-life adversity on the coupling of structural and functional brain connectivity across childhood

SY Chan, ZM Ngoh, ZY Ong, AL Teh, MZL Kee… - Nature Mental …, 2024 - nature.com
Early-life adversity (ELA) exposure is suggested to accelerate development. However, the
influence of ELA on neurodevelopmental trajectories has not been assessed directly but …

Spatial and temporal pattern of structure–function coupling of human brain connectome with development

G Feng, Y Wang, W Huang, H Chen, J Cheng, N Shu - eLife, 2024 - elifesciences.org
Brain structural circuitry shapes a richly patterned functional synchronization, supporting for
complex cognitive and behavioural abilities. However, how coupling of structural …

[HTML][HTML] Structural and functional connectome relationships in early childhood

Y Hong, E Cornea, JB Girault, M Bagonis… - Developmental …, 2023 - Elsevier
There is strong evidence that the functional connectome is highly related to the white matter
connectome in older children and adults, though little is known about structure-function …

[HTML][HTML] Aberrant dynamic functional-structural connectivity coupling of large-scale brain networks in poststroke motor dysfunction

X Liu, S Qiu, X Wang, H Chen, Y Tang, Y Qin - NeuroImage: Clinical, 2023 - Elsevier
Background and purpose Stroke may lead to widespread functional and structural
reorganization in the brain. Several studies have reported a potential correlation between …

[HTML][HTML] Functional activity of the caudate mediates the relation between early childhood microstructural variations and elevated metabolic syndrome scores

P Huang, MT Tint, M Lee, ZM Ngoh, P Gluckman… - NeuroImage, 2023 - Elsevier
Background Metabolic syndrome score in children assesses the risk of developing
cardiovascular disease in future. We aim to probe the role of the caudate in relation to the …

[HTML][HTML] Variations in Cortical Functional Gradients Relate to Dimensions of Psychopathology in Preschool Children

TT Nguyen, X Qian, EKK Ng, MQW Ong… - Journal of the American …, 2024 - Elsevier
Objective It is unclear how the functional brain hierarchy is organized in preschool-aged
children, and whether alterations in the brain organization are linked to mental health in this …

Associations Between Executive Functioning, Behavioral Functioning, and Adaptive Functioning Difficulties in Wiedemann–Steiner Syndrome

R Ng, HT Bjornsson, JA Fahrner… - Archives of Clinical …, 2024 - academic.oup.com
Abstract Objectives Wiedemann–Steiner syndrome (WSS) is a neurogenetic disorder
caused by heterozygous variants in KMT2A. Recent investigations suggest increased …

Individualized identification value of stress-related network structural-functional properties and HPA axis reactivity for subthreshold depression

Y He, B Zhao, Z Liu, Y Hu, J Song, J Wu - Translational Psychiatry, 2024 - nature.com
Accumulating studies have highlighted the links between stress-related networks and the
HPA axis for emotion regulation and proved the mapping associations between altered …

Regional structural-functional connectivity coupling in major depressive disorder is associated with neurotransmitter and genetic profiles

T Chu, X Si, H Xie, H Ma, Y Shi, W Yao, D Xing… - Biological …, 2025 - Elsevier
Background Abnormalities in structural-functional connectivity (SC-FC) coupling have been
identified globally in patients with major depressive disorder (MDD). However, investigations …

[HTML][HTML] Examining the associations between microglia genetic capacity, early life exposures and white matter development at the level of the individual

SY Chan, E Fitzgerald, ZM Ngoh, J Lee, J Chuah… - Brain, Behavior, and …, 2024 - Elsevier
There are inter-individual differences in susceptibility to the influence of early life
experiences for which the underlying neurobiological mechanisms are poorly understood …