Short, synthetic peptides that are displayed by major histocompatibility complex I (MHC I)
can stimulate CD8 T cells in vivo to destroy virus-infected or cancer cells. The development …

Amidines are a structural surrogate for peptide bonds, yet have received considerably little
attention in peptides due to limitations in existing methods to access them. The synthetic …

A sulfur-involved ligation for thioamide quasi-peptides was developed via amino acids and
amino aldehydes coupling. The key to the transformation was the chelation of copper with …

Thioamides are naturally occurring isosteres of amide bonds in which the chalcogen atom of
the carbonyl is changed from oxygen to sulfur. This substitution gives rise to altered …

Environmentally friendly ynamide-mediated thioamidation of monothiocarboxylic acids with
amines or ammonium hydroxide for the syntheses of thioamides and primary thioamides is …

Site Specific Preparation of N‐Glycosylated Peptides: Thioamide‐Directed Activation of
Aspartate - Taresh - 2022 - Angewandte Chemie - Wiley Online Library Skip to Article Content …

During the last two decades, organosulfur compounds have been used in the field of
transition metal catalysis. Some of such compounds are known for their ability to withstand …

Amino acid side chains are key to fine‐tuning the microenvironment polarity in proteins
composed of polar amide bonds. Here, we report that substituting an oxygen atom of the …

Diketopiperazine (DKP) derived cyclic amidine structures widely exist in peptide natural
products according to the genome mining result. The largely unknown bioactivity and mode …

The thioamide is a naturally-occurring single atom substitution of the canonical amide bond.
The exchange of oxygen to sulfur alters the amide's physical and chemical characteristics …