RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Pancreatic cancer is one of the most fatal malignancies and the seventh leading cause of
cancer-related deaths related to late diagnosis, poor survival rates, and high incidence of …

Ferroptosis is a newly-discovered cell death mechanism involved in the progression of
various tumors, the role of noncoding RNAs (ncRNAs) in it was relatively less explored. This …

Serum-and glucocorticoid-regulated kinases (SGKs) are members of the AGC family of
serine/threonine kinases, consisting of three isoforms: SGK1, SGK2, and SGK3. SGK1 was …

Breast cancer is a heterogeneous disease classified into four main subtypes with different
clinical outcomes, such as patient survival, prognosis, and relapse. Current genetic tests for …

Abstract Poly (rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized
by its ability to interact with poly (C) with high affinity in a sequence-specific manner. PCBP2 …

Simple Summary Pancreatic adenocarcinoma (PAAD) is one of the most common tumors of
the gastrointestinal tract and is difficult to diagnose and treat due to tumor heterogeneity and …

Cancer remains the second leading cause of death worldwide, surpassed only by
cardiovascular disease. From the different types of cancer, pancreatic cancer (PaC) has one …

Aberrant RNA alternative splicing (AS) variants play critical roles in tumorigenesis and
prognosis in human cancers. Here, we conducted a comprehensive profiling of aberrant AS …

Pancreatic duct adenocarcinoma (PDAC) is a highly malignant type of cancer with a low five‑
year survival rate. Gene alterations are crucial to the molecular pathogenesis of PDAC …