Emerging roles for hyaluronidase in cancer metastasis and therapy

CO McAtee, JJ Barycki, MA Simpson - Advances in cancer research, 2014 - Elsevier
Hyaluronidases are a family of five human enzymes that have been differentially implicated
in the progression of many solid tumor types, both clinically and in functional studies …

Bladder cancer detection and monitoring: assessment of urine-and blood-based marker tests

S Goodison, CJ Rosser, V Urquidi - Molecular diagnosis & therapy, 2013 - Springer
Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and
management of this disease can be very successful if the disease is detected early. The …

Amino-functionalized green fluorescent carbon dots as surface energy transfer biosensors for hyaluronidase

S Liu, N Zhao, Z Cheng, H Liu - Nanoscale, 2015 - pubs.rsc.org
Amino-functionalized fluorescent carbon dots have been prepared by hydrothermal
treatment of glucosamine with excess pyrophosphate. The produced carbon dots showed …

Detection of bladder cancer using novel DNA methylation biomarkers in urine sediments

W Chung, J Bondaruk, J Jelinek, Y Lotan, S Liang… - … , biomarkers & prevention, 2011 - AACR
Abstract Background: Bladder cancer (BCa) remains a lethal malignancy that can be cured if
detected early. DNA hypermethylation is a common epigenetic abnormality in cancer that …

[HTML][HTML] Urine cytology and adjunct markers for detection and surveillance of bladder cancer

PS Sullivan, JB Chan, MR Levin… - American journal of …, 2010 - ncbi.nlm.nih.gov
Urine cytology coupled with cystoscopic examination has been and remains the standard in
the initial evaluation of lower urinary tract lesions to rule out bladder cancer. However …

Association of hyaluronic acid family members (HAS1, HAS2, and HYAL‐1) with bladder cancer diagnosis and prognosis

MW Kramer, DO Escudero, SD Lokeshwar… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Cancer biomarkers are the backbone for the implementation of
individualized approaches to bladder cancer (BCa). Hyaluronic acid (HA) and all 7 members …

Survivin signaling in clinical oncology: a multifaceted dragon

JR Kanwar, SK Kamalapuram… - Medicinal research …, 2013 - Wiley Online Library
Survivin is an inhibitor of apoptosis protein (IAP) family member preferentially expressed in a
myriad of clinical cancers. The complex functional mechanism and regulatory roles of …

Nucleic acid-based biomarkers in body fluids of patients with urologic malignancies

B Ralla, C Stephan, S Meller, D Dietrich… - Critical reviews in …, 2014 - Taylor & Francis
This review focuses on the promising potential of nucleic acids in body fluids such as blood
and urine as diagnostic, prognostic, predictive and monitoring biomarkers in urologic …

Direct detection of hyaluronidase in urine using cationic gold nanoparticles: a potential diagnostic test for bladder cancer

AI Nossier, S Eissa, MF Ismail, MA Hamdy… - Biosensors and …, 2014 - Elsevier
Hyaluronidase (HAase) was reported as a urinary marker of bladder cancer. In this study, a
simple colorimetric gold nanoparticle (AuNP) assay was developed for rapid and sensitive …

Noninvasive urine-based tests to diagnose or detect recurrence of bladder cancer

M Charpentier, C Gutierrez, T Guillaudeux, G Verhoest… - Cancers, 2021 - mdpi.com
Simple Summary Bladder cancer (BC) is the tenth most common cancer worldwide, with
approximatively 550,000 new cases and 200,000 deaths in 2018. BC is divided into two …