Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism
Autism spectrum disorder (ASD) involves substantial genetic contributions. These
contributions are profoundly heterogeneous but may converge on common pathways that …
contributions are profoundly heterogeneous but may converge on common pathways that …
The valproic acid-induced rodent model of autism
C Nicolini, M Fahnestock - Experimental neurology, 2018 - Elsevier
Autism is a lifelong neurodevelopmental disorder characterized by impairments in social
communication and interaction and by repetitive patterns of behavior, interests and activities …
communication and interaction and by repetitive patterns of behavior, interests and activities …
An aberrant precision account of autism
Autism is a neurodevelopmental disorder characterized by problems with social-
communication, restricted interests and repetitive behavior. A recent and thought-provoking …
communication, restricted interests and repetitive behavior. A recent and thought-provoking …
Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
Genetic and genomic approaches have implicated hundreds of genetic loci in
neurodevelopmental disorders and neurodegeneration, but mechanistic understanding …
neurodevelopmental disorders and neurodegeneration, but mechanistic understanding …
Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
An update on pharmacotherapy of autism spectrum disorder in children and adolescents
To date, no medication is proven to be effective in treating core symptoms of autism
spectrum disorder (ASD). Psychotropic medications are widely used to target emotional and …
spectrum disorder (ASD). Psychotropic medications are widely used to target emotional and …
Environmental toxicants and autism spectrum disorders: a systematic review
DA Rossignol, SJ Genuis, RE Frye - Translational psychiatry, 2014 - nature.com
Although the involvement of genetic abnormalities in autism spectrum disorders (ASD) is
well-accepted, recent studies point to an equal contribution by environmental factors …
well-accepted, recent studies point to an equal contribution by environmental factors …
Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice
Q Wang, Y Kong, DY Wu, JH Liu, W Jie, QL You… - Nature …, 2021 - nature.com
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder. The
mechanisms underlying ASD are unclear. Astrocyte alterations are noted in ASD patients …
mechanisms underlying ASD are unclear. Astrocyte alterations are noted in ASD patients …