Vaccines: past, present and future

SA Plotkin - Nature medicine, 2005 - nature.com
The vaccines developed over the first two hundred years since Jenner's lifetime have
accomplished striking reductions of infection and disease wherever applied. Pasteur's early …

Developments in liposomal drug delivery systems

N Maurer, DB Fenske, PR Cullis - Expert opinion on biological …, 2001 - Taylor & Francis
Liposomes are the leading drug delivery systems for the systemic (iv.) administration of
drugs. There are now liposomal formulations of conventional drugs that have received …

Improvement of different vaccine delivery systems for cancer therapy

A Bolhassani, S Safaiyan, S Rafati - Molecular cancer, 2011 - Springer
Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …

Recent developments in adjuvants for vaccines against infectious diseases

DT O'Hagan, ML MacKichan, M Singh - Biomolecular engineering, 2001 - Elsevier
New generation vaccines, particularly those based on recombinant proteins and DNA, are
likely to be less reactogenic than traditional vaccines, but are also less immunogenic …

Combinatorial prospects of nano-targeted chemoimmunotherapy

CG Da Silva, F Rueda, CW Löwik, F Ossendorp… - Biomaterials, 2016 - Elsevier
Despite the significant increase in our knowledge on cancer initiation and progression, and
the development of novel cancer treatments, overall patient survival rates have thus far only …

Allogeneic tumor cell vaccines: the promise and limitations in clinical trials

S Srivatsan, JM Patel, EN Bozeman… - Human vaccines & …, 2014 - Taylor & Francis
The high mortality rate associated with cancer and its resistance to conventional treatments
such as radiation and chemotherapy has led to the investigation of a variety of anti-cancer …

[图书][B] Microscopy, immunohistochemistry, and antigen retrieval methods: for light and electron microscopy

MA Hayat - 2002 - books.google.com
Histochemistry deals with the activities of chemical components in cells, and
immunohistochemistry addresses the function of cell types in tissue or organs, such as those …

[图书][B] Molecular biology of cancer

F Macdonald, C Ford, A Casson - 2004 - taylorfrancis.com
Molecular Biology of Cancer has been extensively revised and covers heredity cancer,
microarray technology and increased study of childhood cancers. It continues to provide a …

Role of 4-1BB: 4-1BB ligand in cancer immunotherapy

ATC Cheuk, GJ Mufti, B Guinn - Cancer gene therapy, 2004 - nature.com
The activation of T cells plays a central role in antitumor immunity. In order to activate naïve
T cells, two key signals are required. Signal one is provided through the T-cell receptor …

Needle-free epidermal powder immunization

D Chen, YF Maa, JR Haynes - Expert Review of Vaccines, 2002 - Taylor & Francis
Due to the presence of a network of antigen-presenting cells and other cells with innate and
adaptive immune functions, the skin is both a sensitive immune organ and a practical target …