Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

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Background Preterm newborns are at high risk of developing neurodevelopmental deficits
caused by neuroinflammation leading to perinatal brain injury. Human Wharton's jelly …

The fetal origins of adult disease (FOAD) hypothesis, which was proposed by David Barker
in the United Kingdom in the late 1980s, posited that adult chronic diseases originated from …

The neurovascular unit (NVU) is a relatively recent concept in neuroscience that broadly
describes the relationship between brain cells and their blood vessels. The NVU …

Background Therapeutic hypothermia reduces the risk of death, or moderate to severe
neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic …

Objectives: Identify maternal and fetal risk factors during prenatal care to prevent potential
birth asphyxia. Screen newborns promptly for signs of birth asphyxia using APGAR scores …

Good quality sleep of sufficient duration is vital for optimal physiological function and our
health. Sleep deprivation is associated with impaired neurocognitive function and emotional …

The preterm newborn is at significant risk of neural injury and impaired neurodevelopment.
Infants with mild or no evidence of injury may also be at risk of altered brain development …

Methods We included full articles and book chapters published in English on PubMed with
references to “hypoxic ischemic encephalopathy”,“birth asphyxia”,“therapeutic hypothermia” …