Diabetic retinopathy, a vascular and inflammatory disease: therapeutic implications

F Semeraro, F Morescalchi, A Cancarini, A Russo… - Diabetes & …, 2019 - Elsevier
Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and
the leading cause of visual impairment in the working-age population in the Western world …

The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective

P Mammadzada, PM Corredoira, H André - Cellular and Molecular Life …, 2020 - Springer
Understanding the mechanisms that underlie age-related macular degeneration (AMD) has
led to the identification of key molecules. Hypoxia-inducible transcription factors (HIFs) have …

[HTML][HTML] Preparation of polycaprolactone and polymethacrylate nanofibers for controlled ocular delivery of ketorolac tromethamine: Pharmacokinetic study in Rabbit's …

S Taghe, S Mirzaeei, M Bagheri - European Journal of Pharmaceutical …, 2024 - Elsevier
Ophthalmitis is an inflammation of the eye triggered by various conditions including
diseases, allergy, trauma, or surgery. Management of this condition usually includes …

Topical nonsteroidal anti‐inflammatory drugs for macular edema

A Russo, C Costagliola, L Delcassi… - Mediators of …, 2013 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are nowadays widely used in
ophthalmology to reduce eye inflammation, pain, and cystoid macular edema associated …

Topical treatment for retinal degenerative pathologies: a systematic review

L Samoilă, O Voștinaru, E Dinte, AE Bodoki… - International Journal of …, 2023 - mdpi.com
The topical administration of medicines is the preferred route in ocular therapy, at least for
the anterior segment of the eye. However, the eye's inherent functional and biological …

Inflammaging: should this term be suitable for age related macular degeneration too?

CE Gallenga, F Parmeggiani, C Costagliola… - Inflammation …, 2014 - Springer
Introduction Inflammaging is a phenomenon triggered by the conjunction of chronic
repetitive and subclinical inflammation from external aggressors and internal inflammatory …

Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled …

H Nikkhah, R Niazpour Moez, M Entezari… - Graefe's Archive for …, 2021 - Springer
Purpose To evaluate the additional effect of ketorolac eye drops on therapeutic effects of
intravitreal Bevacizumab in patients with diabetic macular edema (DME) Methods In a …

Efficacy and vitreous levels of topical NSAIDs

F Semeraro, A Russo, E Gambicorti… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly
prescribed medications and are routinely used for their analgesic, antipyretic, and anti …

Treatment of exudative age‐related macular degeneration with aflibercept combined with pranoprofen eye drops or nutraceutical support with omega‐3: A …

F Semeraro, E Gambicordi, A Cancarini… - British journal of …, 2019 - Wiley Online Library
Aims The aim of this study was to determine whether a combination of intravitreal aflibercept
(IVA) and pranoprofen eyedrops or nutraceutical support provides additional benefit over …

Combinatorial treatment with topical NSAIDs and anti-VEGF for age-related macular degeneration, a meta-analysis

S Li, A Hu, W Wang, X Ding, L Lu - Plos one, 2017 - journals.plos.org
Inflammation is a key pathogenic factor in age-related macular degeneration (AMD).
However, the clinical importance of combining anti-VEGF agents and topical NSAIDs to …