Glaucoma is a group of heterogeneous optic neuropathies with complex genetic basis.
Among the three principle subtypes of glaucoma, primary open angle glaucoma (POAG) …

Glaucoma represents a heterogeneous group of optic neuropathies, with different genetic
bases. It can affect all ages generally with a rise in intra-ocular pressure. Three major types …

Purpose To characterize the biophysical properties of an artificial vitreous body substitute
(VBS), which consists of a biocompatible, cross-linked, hyaluronic acid (HA)-based …

Myocilin is a secreted glycoprotein of unknown function that is ubiquitously expressed in
many human organs, including the eye. Mutations in this protein produce glaucoma, a …

Glaucoma, which is a complex heterogeneous disease, presents an ideal case for genetic
investigation. Primary open‐angle glaucoma (POAG) is the commonest subtype and will be …

The categorization of genes by structural distinctions relevant to biological characteristics is
very important for understanding of gene functions and predicting functional implications of …

Background Glaucoma is the world's second leading cause of bilateral blindness with
progressive loss of vision due to retinal ganglion cell death. Myocilin has been associated …

Purpose: Glaucoma is the second leading cause of blindness worldwide after cataract.
Defects in the myocilin gene (MYOC) have been shown to be associated with Primary Open …

METHODS Collection of aqueous humor: This study was approved by the Mayo Clinic
Institutional Review Board, and conforms to the Declaration of Helsinki. Human aqueous …

PURPOSE: To identify olfactomedin domain containing proteins, which are expressed in the
eye and have similarity to myocilin, to test as potential candidates for eye diseases. Most of …