Background Levetiracetam has been widely used as a treatment option for different types of
epilepsy in both adults and children. Because of its large between-subject variability, several …

Background Subcutaneous drug administration is an interesting approach for symptom
control in hospice and palliative care. However, most drugs have no marketing authorization …

Background: Levetiracetam has a favorable pharmacology profile to be used
subcutaneously. However, its subcutaneous use is still considered off-label as this is beyond …

Objectives: The aim of this study is to report the results of a second cycle audit of the use of
subcutaneous levetiracetam (Keppra®) and an updated literature review of management of …

This narrative review aims to summarise the information available on the use of
subcutaneous (SC) levetiracetam (LEV) in the adult palliative care setting using clinical …

Background: Seizures are common in palliative care patients and its control is essential in
the management of these patients as it helps to reduce suffering at the end of life …

Os cuidados paliativos têm como intuito a melhoria da qualidade de vida dos doentes que
se defrontam com doenças graves e/ou avançadas, incuráveis ou progressivas. A gestão …

Palliative care patients experience seizures in different stages of their disease and may not
tolerate oral medications toward the end of life. Subcutaneous infusions of levetiracetam and …

To understand the mechanism of action of drugs, it is necessary to have a thorough
knowledge of different mechanisms identified and established for endogenous …

We present two cases, in which end-of-life patients were inadvertently treated with bolus
infusions of undiluted subcutaneous levetiracetam. The patients were treated for three and …