COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases
Although most autoimmune diseases are considered to be CD4 T cell-or antibody-mediated,
many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma …
many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma …
Recent advances in novel lateral flow technologies for detection of COVID-19
The development of reliable and robust diagnostic tests is one of the most efficient methods
to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe …
to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe …
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In
November 2021, the Omicron variant was discovered and immediately classified as a …
November 2021, the Omicron variant was discovered and immediately classified as a …
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection
Background Monitoring the adaptive immune responses during the natural course of severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection provides useful …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection provides useful …
[HTML][HTML] Neutralizing antibodies targeting SARS-CoV-2 spike protein
S Xiaojie, L Yu, Y Guang, Q Min - Stem cell research, 2021 - Elsevier
SARS-CoV-2 causing the worldwide pandemic has changed people's life in multiple aspects
dramatically since it's first identified in Wuhan, China at the end of 2019. While the numbers …
dramatically since it's first identified in Wuhan, China at the end of 2019. While the numbers …
Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …
SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact
The trimeric spike (S) glycoprotein, which protrudes from the SARS-CoV-2 viral envelope,
binds to human ACE2, initiated by at least one protomer's receptor binding domain (RBD) …
binds to human ACE2, initiated by at least one protomer's receptor binding domain (RBD) …
Developing recombinant antibodies by phage display against infectious diseases and toxins for diagnostics and therapy
KDR Roth, EV Wenzel, M Ruschig, S Steinke… - Frontiers in cellular …, 2021 - frontiersin.org
Antibodies are essential molecules for diagnosis and treatment of diseases caused by
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
Molecular rationale for SARS-CoV-2 spike circulating mutations able to escape bamlanivimab and etesevimab monoclonal antibodies
The purpose of this work is to provide an in silico molecular rationale of the role eventually
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …
Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …