The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease

DM Ouwens, H Sell, S Greulich… - Journal of cellular and …, 2010 - Wiley Online Library
Introduction• Fat depots around the heart and vasculature‐Definitions‐Epicardial adipose
tissue‐Perivascular adipose tissue‐Pericardial adipose tissue• Physiological function of …

The role of adipocytes in the modulation of iron metabolism in obesity

S Coimbra, C Catarino, A Santos‐Silva - Obesity reviews, 2013 - Wiley Online Library
A tight relationship between iron deficiency and obesity is known to exist. The chronic low‐
grade inflammation that characterizes obesity enhances hepcidin production, the principal …

Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: a case control study

M Sanad, M Osman, A Gharib - Italian journal of pediatrics, 2011 - Springer
Background Recently, hepcidin expression in adipose tissue has been described and
shown to be increased in patients with severe obesity. We tried to assess the effect of …

Transferrin receptor 1 in the zoonosis and pathogenesis of New World hemorrhagic fever arenaviruses

H Choe, S Jemielity, J Abraham… - Current opinion in …, 2011 - Elsevier
At least five New World arenaviruses cause severe human hemorrhagic fevers. These
viruses are transmitted to humans through contact with their respective South American …

Potential role of selenium in alleviating obesity-related iron dyshomeostasis

G Liu, J Li, B Pang, Y Li, F Xu, N Liao… - Critical Reviews in …, 2023 - Taylor & Francis
Obesity is a serious health problem in modern life and increases the risk of many
comorbidities including iron dyshomeostasis. In contrast to malnourished anemia, obesity …

Transcriptome and molecular endocrinology aspects of epicardial adipose tissue in cardiovascular diseases: a systematic review and meta‐analysis of observational …

Z Maghbooli, A Hossein-Nezhad - BioMed research …, 2015 - Wiley Online Library
The objective of this study was to perform a systematic review of published literature on
differentially expressed genes (DEGs) in human epicardial adipose tissue (EAT) to identify …

Iron primes 3T3-L1 adipocytes to a TLR4-mediated inflammatory response

S Chirumbolo, AP Rossi, V Rizzatti, E Zoico… - Nutrition, 2015 - Elsevier
Objective Iron participates in several mechanisms involving inflammation and innate
immunity, yet the dysregulation of its homeostasis is a major cause of metabolic syndrome …

Chronic intermittent hypobaric hypoxia improves iron metabolism disorders via the IL-6/JAK2/STAT3 and Epo/STAT5/ERFE signaling pathways in metabolic syndrome …

F Cui, J Sun, H Mi, B Li, L Tang, R Wang, Y Du… - Journal of Trace …, 2023 - Elsevier
Aim Our previous study demonstrated that chronic intermittent hypobaric hypoxia (CIHH)
improved iron metabolism disorder in obese rats through the downregulation of hepcidin …

Obesity and iron deficiency in chronic kidney disease: the putative role of hepcidin

PA Sarafidis, A Rumjon, HL MacLaughlin… - Nephrology Dialysis …, 2012 - academic.oup.com
Hepcidin is a 25-amino acid peptide with a defensinlike structure that is primarily
synthesized in hepatocytes [1, 2]. It was independently isolated∼ 10 years ago by two …

Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo

L Tussing-Humphreys, KN Frayn… - The Scientific World …, 2011 - Wiley Online Library
Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the
liver but is also expressed, at the mRNA‐level, in periphery tissues including the …